Table 2 Comparison of the FPS and LPS stage within DuoStim protocol
Characteristic | FPS stage n = 304 | LPS stage n = 304 | P value |
|---|---|---|---|
Total dose of Gonadotrophin (IU) | 1359.51 ± 1135.84 | 1678.25 ± 882.64* | 0.000 |
Duration of stimulation (days) | 6.10 ± 3.48 | 7.16 ± 3.12* | 0.000 |
E2 on HCG day (pg/ml) | 669.27 ± 527.86 | 1377.95 ± 1155.53* | 0.000 |
P4 on HCG day (ng/ml) | 0.63 ± 0.95 | 14.98 ± 14.35* | 0.000 |
LH on HCG day (IU/L) | 5.75 ± 5.50 | 3.94 ± 4.80* | 0.000 |
Follicles≥14 mm on HCG day | 1.46 ± 0.85 | 3.27 ± 2.94* | 0.000 |
Follicles 10-13 mm on HCG day | 0.61 ± 1.01 | 1.39 ± 2.06* | 0.000 |
Follicles≤10 mm on HCG day | 2.07 ± 1.47 | 4.66 ± 4.49* | 0.000 |
No. of oocyte retrieved | 1.71 ± 1.30 | 3.58 ± 4.54* | 0.000 |
No. of normal fertilized oocyte | 1.09 ± 0.91 | 2.25 ± 2.85* | 0.000 |
No. of cleaved embryos | 1.05 ± 0.91 | 2.20 ± 2.80* | 0.000 |
No. of cryopreserved embryos | 0.90 ± 0.78 | 1.82 ± 2.54* | 0.000 |
No. of good quality embryos | 0.79 ± 0.76 | 1.62 ± 2.40* | 0.000 |
Fertilization rate (%) | 62.43% | 62.50% | 0.978 |
Cleaved embryos rate (%) | 98.77% | 98.24% | 0.531 |
Rate of cryopreserved embryos (%) | 85.93% | 82.63% | 0.188 |
Rate of good quality embryos (%) | 74.69% | 73.80% | 0.766 |
Formed blastulation rate (%) | 48.48% | 67.42%* | 0.037 |
Lesser quality embryos formed blastulation rate (%) | 23.08%(3/13) | 32.08%(17/53) | 0.527 |
Pregnancy rate per FET (%) | 26.42%(14/53) | 47.27%(52/110)* | 0.011 |
Pregnancy rate per oocyte retrieval (%) | 7.37%(14/190) | 24.41%(52/213)* | 0 |
Implantation rate (%) | 14.48% (21/145) | 29.81% (79/265)* | 0.001 |
Spontaneous abortion rate (%) | 42.85%(6/14) | 21.15%(11/52) | 0.099 |