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Table 3 Main results for the MTHFR 1298A/C polymorphism in the meta-analysis

From: Association of the MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis

Variables Cases/Controls CC vs. AA CA vs. AA CC + CA vs. AA CC vs. CA + AA
OR(95% CI) P * OR (95% CI) P * OR (95% CI) P * OR (95% CI) P *
Total 5893/6303 1.23 (0.97, 1.55) 0.002 1.08 (0.96, 1.20) p = 0.031 1.10 (0.99, 1.24) 0.014 0.86 (0.68, 1.08) 0.000
Ethnicity Cases/Controls TT vs. CC TC vs. CC TT + TC vs. CC TT vs. TC + CC
OR(95% CI) P * OR (95% CI) P * OR (95% CI) P * OR (95% CI) P *
Asian 4918/4782 1.23 (0.92, 1.64) 0.010 1.11 (0.99, 1.25) 0.227 1.13 (0.99, 1.30) 0.050 0.87 (0.67, 1.13) 0.006
Caucasian 1065/1521 1.21 (0.96, 1.53) 0.258 0.88 (0.74, 1.05) 0.370 0.91 (0.78, 1.07) 0.671 0.82 (0.52, 1.30) 0.096
  1. *P value of the chi- square test for heterogeneity