Skip to main content

Table 2 Main results for the MTHFR 677C > T polymorphism in the meta-analysis

From: Association of the MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis

Variables Cases/Controls TT vs. CC TC vs. CC TT + TC vs. CC TT vs. TC + CC
OR(95% CI) P * OR (95% CI) P * OR (95% CI) P * OR (95% CI) P *
Total 9662/9154 1.62 (1.36, 1.93) 0.00 1.28 (1.14, 1.44) 0.00 1.37 (1.21, 1.55) 0.00 0.70 (0.61, 0.81) 0.00
Ethnicity Cases/Controls TT vs. CC TC vs. CC TT + TC vs. CC TT vs. TC + CC
OR(95% CI) P * OR (95% CI) P * OR (95% CI) P * OR (95% CI) P *
Asian 7989/6887 1.78 (1.48–2.16) 0.01 1.35 (1.20–1.53) 0.00 1.46 (1.29–1.65) 0.00 0.66 (0.56–0.77) 0.08
Caucasian 1673/2267 2.23 (0.84–1.80) 0.00 1.02 (0.83–1.27) 0.03 1.08 (0.86–1.36) 0.00 0.87 (0.63–1.20) 0.00
  1. *P value of the chi- square test for heterogeneity