Establishment of a WHO Reference Reagent for anti-Mullerian hormone

Table 3 Geometric mean laboratory estimates for the AMH content in ampoules A, B and C as provided by the 16 methods which met the validity criteria

Lab	Sample A	Sample C	GM(A,C)	Sample B	Ratio of B to GM(A,C)
1	337	335	336	150	0.45
2	623	624	624	283	0.45
3	1094	1074	1084	548	0.51
4	523	542	533	293	0.55
5	520	537	528	284	0.54
6	1182	1133	1157	554	0.48
7	484	456	470	252	0.54
8
9	546	553	549	298	0.54
10
11
12	499	506	502	324	0.65
13	277	288	282	141	0.50
14	481	470	475	253	0.53
15	453	471	462	268	0.58
16	461	467	464	203	0.44
17
18
19	379	381	380	210	0.55
20	472	498	485	312	0.64
21	410	432	421	228	0.54
Geometric Mean	508	513	511	269	0.53
95% Confidence Limits	417–619	430–612	426–612	221–328	0.50–0.56
GCV	45%	41%	42%	45%	12%
Robust Geometric Mean	487	494	489	265	0.53

Ampoules A and C are coded duplicates of the proposed reference material, 16/190. Ampoule B is a comparator preparation containing approximately half the AMH content

ISSN: 1477-7827