Table 1 Differentially expressed proteins in the sixth week after heat-treated group compared with those in the control group
From: Effect of transient scrotal hyperthermia on human sperm: an iTRAQ-based proteomic analysis
No. | Gene | Accession | Name | Fold change (avg) |
|---|---|---|---|---|
1 | AKAP4 | Q5JQC9 | A-kinase anchor protein 4 | 0.60675 |
2 | ODF2 | Q5BJF6 | Outer dense fiber protein 2 | 0.63015 |
3 | HK1 | P19367 | Hexokinase-1 | 0.62455 |
4 | CCIN | Q13939 | Calicin | 0.62445 |
5 | GAPDHS | O14556 | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 0.65205 |
6 | TEKT5 | Q96M29 | Tektin-5 | 0.61830 |
7 | FAM71B | Q8TC56 | Protein FAM71B | 0.55335 |
8 | LRRC37B | Q96QE4 | Leucine-rich repeat-containing protein 37B | 0.62535 |
9 | TPI1 | P60174 | Triosephosphate isomerase | 0.59305 |
10 | ODF1 | Q14990 | Outer dense fiber protein 1 | 0.60095 |
11 | GLUL | P15104 | Glutamine synthetase | 0.65995 |
12 | SPESP1 | Q6UW49 | Sperm equatorial segment protein 1 | 0.63020 |
13 | RAB2A | P61019 | Ras-related protein Rab-2A | 0.62420 |
14 | ZPBP | Q9BS86 | Zona pellucida-binding protein 1 | 0.57560 |
15 | ACTRT2 | Q8TDY3 | Actin-related protein T2 | 0.66370 |
16 | RSPH9 | Q9H1X1 | Radial spoke head protein 9 homolog | 0.65810 |
17 | FAM71A | Q8IYT1 | Protein FAM71A | 0.59755 |
18 | MENT | Q9BUN1 | Protein MENT | 0.55490 |
19 | ACTL9 | Q8TC94 | Actin-like protein 9 | 0.65075 |
20 | CYCL1 | P35663 | Cylicin-1 | 0.57220 |
21 | CYCL2 | Q14093 | Cylicin-2 | 0.50275 |
22 | VRK3 | Q8IV63 | Inactive serine/threonine-protein kinase VRK3 | 0.62290 |
23 | ATP1B3 | P54709 | Sodium/potassium-transporting ATPase subunit beta-3 | 0.63620 |
24 | FNDC8 | Q8TC99 | Fibronectin type III domain-containing protein 8 | 0.54235 |
25 | PPIL6 | Q8IXY8 | Peptidyl-prolyl cis-trans isomerase-like 6 | 0.64450 |
26 | SMCP | P49901 | Sperm mitochondrial-associated cysteine-rich protein | 0.51795 |
27 | SLC2A5 | P22732 | Solute carrier family 2, facilitated glucose transporter member 5 | 0.65610 |
28 | PFN3 | P60673 | Profilin-3 | 0.58565 |
29 | TMEM190 | Q8WZ59 | Transmembrane protein 190 | 0.60795 |
30 | SPATA31D1 | Q6ZQQ2 | Spermatogenesis-associated protein 31D1 | 0.66080 |
31 | DYDC1 | Q8WWB3 | DPY30 domain-containing protein 1 | 0.65775 |
32 | CD46 | P15529 | Membrane cofactor protein | 0.63320 |
33 | EFCAB3 | Q8N7B9 | EF-hand calcium-binding domain-containing protein 3 | 0.59870 |
34 | HNPNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | 1.89130 |
35 | CLGN | O14967 | Calmegin | 2.11610 |
36 | CANX | P27824 | Calnexin | 1.81915 |
37 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | 1.84040 |
38 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | 1.98985 |
39 | DDX4 | Q9NQI0 | Probable ATP-dependent RNA helicase DDX4 | 1.72575 |
40 | RCN2 | Q14257 | Reticulocalbin-2 | 1.67800 |
41 | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | 1.91345 |
42 | DDX39A | O00148 | ATP-dependent RNA helicase DDX39A | 1.95795 |
43 | HNRNPK | P61978 | Heterogeneous nuclear ribonucleoprotein K | 1.94255 |
44 | NPM1 | P06748 | Nucleophosmin | 1.80460 |
45 | DDX17 | Q92841 | Probable ATP-dependent RNA helicase DDX17 | 1.76955 |
46 | UMOD | P07911 | Uromodulin | 2.17185 |
47 | HNRNPA3 | P51991 | Heterogeneous nuclear ribonucleoprotein A3 | 2.18345 |
48 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | 1.63640 |
49 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | 1.70640 |
50 | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | 1.74625 |
51 | RAN | P62826 | GTP-binding nuclear protein Ran | 1.85995 |
52 | DHX15 | O43143 | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 | 1.76235 |
53 | ELAVL1 | Q15717 | ELAV-like protein 1 | 1.66060 |
54 | HNRNPF | P52597 | Heterogeneous nuclear ribonucleoprotein F | 2.04530 |
55 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | 2.13890 |
56 | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | 2.00500 |
57 | SF3B3 | Q15393 | Splicing factor 3B subunit 3 | 1.82035 |
58 | RBMXL2 | O75526 | RNA-binding motif protein, X-linked-like-2 | 1.60315 |
59 | RBMY1C | P0DJD4 | RNA-binding motif protein, Y chromosome, family 1 member C | 2.45005 |
60 | MYEF2 | Q9P2K5 | Myelin expression factor 2 | 1.66025 |
61 | REG3G | Q6UW15 | Regenerating islet-derived protein 3-gamma | 1.68985 |