Skip to main content

Table 1 Clinical data of patients who underwent PGT or not

From: Clinical outcomes of Preimplantation genetic testing (PGT) application in couples with chromosomal inversion, a study in the Chinese Han population

 

PGT group

Control group

t/x2

P value

No. of Cycles

136

52

Duration of Infertility (year)

2.92 ± 3.25

4.29 ± 2.51

2.751

0.007

Maternal Age

31.23 ± 4.94

31.02 ± 4.78

−0.261

0.794

BMI

24.06 ± 3.66

23.53 ± 3.36

−0.907

0.366

RSA

16 (11.8%)

0 (0.0%)

0.007(Fisher’s exact test)

Uterine Abnormality

31 (22.8%)

10 (19.2%)

0.280

0.597

Hydrosalpinx

13 (9.6%)

7 (13.5%)

0.603

0.438

Uterine Leiomyoma

8 (5.9%)

3 (5.8%)

1.000(Fisher’s exact test)

Previous Pelvic or Intrauterine Surgery

53 (39.0%)

26 (50.0%)

1.878

0.171

COH protocols

Long GnRH agonist

87 (64.0%)

30 (57.7%)

0.631

0.427

Short GnRH agonist

36 (26.5%)

8 (15.4%)

2.579

0.108

GnRH-antagonist

11 (8.1%)

13 (25.0%)

9.661

0.002

other protocols

2 (1.5%)

1 (1.9%)

1.000(Fisher’s exact test)

No. of days of ovarian stimulation

9.74 ± 2.20

9.88 ± 2.12

0.400

0.690

Gonadotropin dose (IU)

1880.19 ± 910.67

1797.36 ± 1051.31

−0.534

0.594

Cumulative Live birth rate

67 (49.3%)

26 (50.0%)

0.008

0.928

First Transfer per cycle

Live birth rate

55 (40.4%)

20 (38.5%)

0.061

0.804

Chemical pregnancy rate

84 (61.8%)

33 (63.5%)

0.046

0.830

Clinical pregnancy rate

73 (53.7%)

27 (51.9%)

0.046

0.829

Ongoing pregnancy rate

70 (51.5%)

27 (51.9%)

0.003

0.956

Miscarriage rate

7 (8.3%)

3 (9.1%)

0.017

0.895