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Table 1 Characteristics and quality assessment scores of eligible studies

From: Androgen levels in the fetal cord blood of children born to women with polycystic ovary syndrome: a meta-analysis

Author

Year

Research type

NOS or AHRQ score

Diagnostic criteria of PCOS

Gestational age

Primary study population

Type of cord blood

Testosterone

Androstenedione

Assay

Original unit

Assay

Original unit

Detti

2019

Cross-sectional

8

NIH criteria

term (≥38w)

PCOS vs non-PCOS women in labor

artery, vein

HPLC/MS

ng/dl

Daan

2017

Case-control

7

Rotterdam criteria

not mentioned

PCOS vs non-PCOS women outpatients

mixed

LC-MS/MS

nmol/L

LC-MS/MS

nmol/L

Caanen

2016

Case-control

8

Rotterdam criteria

not mentioned

PCOS vs non-PCOS in women a part of cohort study

mixed

LC-MS/MS

ng/ml

LC-MS/MS

ng/ml

Maliqueo

2013

Case-control

8

NIH and Rotterdam criteria

term (37-40w)

PCOS outpatients vs healthy women in 12th week of gestation

mixed

RIA

ng/ml

RIA

ng/ml

Mehrabian

2012

Cross-sectional

9

NIH criteria

term

PCOS vs healthy mothers who underwent elective cesarean section

mixed

CLIA

pg/ml

Barry

2010

Case-control

7

Rotterdam criteria

≥38w

PCOS vs non-PCOS women in labour wards

vein

ECL

nmol/L

Anderson

2010

Case-control

8

NIH criteria

>35w

PCOS vs non-PCOS women outpatients

mixed

LC-MS

ng/dl

LC-MS

ng/dl

  1. HPLC/MS high-performance liquid chromatography/mass-spectrometry assay, LC-MS/MS liquid chromatography with tandem mass spectrometer, RIA radioimmunoassay, CLIA chemiluminescent immunoassay, ECL electrochemiluminescence methodology