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Table 2 LC-MS/MS detected metabolites that varied in FF with significant difference

From: Human follicular fluid shows diverse metabolic profiles at different follicle developmental stages

Metabolite RT (min) m/z P values Type
LysoPE(0:0/24:6(6Z,9Z,12Z,15Z,18Z,21Z)) 9.638 613.3383 0.049 down
Gallopamil 9.255 484.2938 0.026 down
Tetrahydropentoxyline 4.265 366.1415 0.047 up
Thelephoric acid 5.07 352.0188 0.039 up
7-methyl-hexadecanoic acid 9.927 270.255 0.040 down
Glutathione (GSH) 1.589 307.0826 0.015 up
4-Carboxy-4-hydroxy-2-oxoadipate 1.043 280.0444 0.002 up
16-Hydroxy hexadecanoic acid 10.212 272.2331 0.041 down
Thymidine 4.311 242.0889 0.011 up
6-(Isopropylthio)purine 7.79 240.067 0.002 up
Acetone 4.216 58.0418 0.049 up
D-Lactic acid 1.284 90.0322 0.0001 down
1,2,3-Tris(1-ethoxyethoxy)propane 6.567 308.222 3.27E-03 down
Fosinopril 5.874 563.2989 3.40E-09 down
Muzanzagenin 8.594 442.2702 6.28E-07 down
3β,7α-Dihydroxy-5-cholestenoate 8.692 454.3049 1.30E-07 down
Z-Arg-Arg-NHMec 5.902 621.3027 3.15E-08 down
Spironolactone 5.918 433.2275 6.36E-06 down
Deoxycorticosterone (DOC) 8.116 330.2213 1.34E-03 down
3-Buten-1-amine 0.776 71.0736 5.33E-05 up
Hypoxanthine 1.698 136.039 6.86E-04 up
(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol 10.786 436.3543 4.33E-04 up
2,5-Dimethyl-1H-pyrrole 0.956 95.0714 3.43E-04 up
5-Androstene-3,17-dione 8.49 286.1953 6.36E-10 up
12,14-Pentacosadiynoic acid 11.285 374.3223 5.70E-04 up
N-(1-Deoxy-1-fructosyl)tyrosine 0.969 360.1529 5.40E-07 up
Dolichyl b-D-glucosyl phosphate 4.878 488.2174 2.39E-04 up
Dehydroepiandrosterone (DHEA) 8.559 288.2111 1.22E-04 up
Monoethylglycylxylidide (MEGX) 4.821 206.1432 3.76E-07 up
3-Hydroxylidocaine 5.37 250.1696 6.60E-06 up
  1. Type: Metabolites in small follicles were compared with those in large follicles, i.e., metabolites in large follicles were used as the control group