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Table 2 LC-MS/MS detected metabolites that varied in FF with significant difference

From: Human follicular fluid shows diverse metabolic profiles at different follicle developmental stages

Metabolite

RT (min)

m/z

P values

Type

LysoPE(0:0/24:6(6Z,9Z,12Z,15Z,18Z,21Z))

9.638

613.3383

0.049

down

Gallopamil

9.255

484.2938

0.026

down

Tetrahydropentoxyline

4.265

366.1415

0.047

up

Thelephoric acid

5.07

352.0188

0.039

up

7-methyl-hexadecanoic acid

9.927

270.255

0.040

down

Glutathione (GSH)

1.589

307.0826

0.015

up

4-Carboxy-4-hydroxy-2-oxoadipate

1.043

280.0444

0.002

up

16-Hydroxy hexadecanoic acid

10.212

272.2331

0.041

down

Thymidine

4.311

242.0889

0.011

up

6-(Isopropylthio)purine

7.79

240.067

0.002

up

Acetone

4.216

58.0418

0.049

up

D-Lactic acid

1.284

90.0322

0.0001

down

1,2,3-Tris(1-ethoxyethoxy)propane

6.567

308.222

3.27E-03

down

Fosinopril

5.874

563.2989

3.40E-09

down

Muzanzagenin

8.594

442.2702

6.28E-07

down

3β,7α-Dihydroxy-5-cholestenoate

8.692

454.3049

1.30E-07

down

Z-Arg-Arg-NHMec

5.902

621.3027

3.15E-08

down

Spironolactone

5.918

433.2275

6.36E-06

down

Deoxycorticosterone (DOC)

8.116

330.2213

1.34E-03

down

3-Buten-1-amine

0.776

71.0736

5.33E-05

up

Hypoxanthine

1.698

136.039

6.86E-04

up

(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol

10.786

436.3543

4.33E-04

up

2,5-Dimethyl-1H-pyrrole

0.956

95.0714

3.43E-04

up

5-Androstene-3,17-dione

8.49

286.1953

6.36E-10

up

12,14-Pentacosadiynoic acid

11.285

374.3223

5.70E-04

up

N-(1-Deoxy-1-fructosyl)tyrosine

0.969

360.1529

5.40E-07

up

Dolichyl b-D-glucosyl phosphate

4.878

488.2174

2.39E-04

up

Dehydroepiandrosterone (DHEA)

8.559

288.2111

1.22E-04

up

Monoethylglycylxylidide (MEGX)

4.821

206.1432

3.76E-07

up

3-Hydroxylidocaine

5.37

250.1696

6.60E-06

up

  1. Type: Metabolites in small follicles were compared with those in large follicles, i.e., metabolites in large follicles were used as the control group