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Table 2 Correlations between mtDNA-CN, 8-OHdG, and clinical variables at baseline

From: Changes in peripheral mitochondrial DNA copy number in metformin-treated women with polycystic ovary syndrome: a longitudinal study

 

mtDNA-CN

8-OHdG

Age

− 0.06283 (0.565)

− 0.07736 (0.476)

BMI

− 0.03618 (0.741)

− 0.10975 (0.312)

Waist circumference

− 0.02719 (0.804)

− 0.04646 (0.669)

Testosterone

0.18848 (0.082)

0.10680 (0.325)

SHBG

0.02572 (0.816)

0.17169 (0.116)

FAI

0.12249 (0.267)

−0.11352 (0.301)

Fasting glucose

0.07002 (0.522)

−0.25524 (0.017)*

Fasting insulin

0.02663 (0.808)

−0.02919 (0.788)

HOMA-IR

0.00987 (0.928)

−0.07668 (0.480)

75 g GTT 2 h

0.14033 (0.312)

−0.06693 (0.634)

GOT

−0.01371 (0.900)

−0.15375 (0.155)

GPT

−0.08597 (0.431)

−0.23377 (0.029)*

SBP

−0.02479 (0.821)

0.01901 (0.861)

DBP

−0.09383 (0.390)

−0.00817 (0.940)

hsCRP

−0.12933 (0.290)

−0.06189 (0.608)

8-OHdG

0.06776 (0.538)

mtDNA-CN

0.06776 (0.538)

  1. Data given as r (p-value); p-value < 0.05 is denoted with *; BMI Body mass index, SHBG Sex hormone binding globulin, FAI Free androgen index, HOMA-IR Homeostatic model assessment-insulin resistance, GTT Glucose tolerance test, GOT/GPT Glutamic oxaloacetic/pyruvic transaminase, SBP Systolic blood pressure, DBP Diastolic blood pressure, hsCRP High sensitivity C-reactive protein, 8-OHdG 8-hydroxy-2-deoxyguanosine, mtDNA-CN Mitochondrial DNA copy number