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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: Downregulation of hsa_circ_0005243 induces trophoblast cell dysfunction and inflammation via the β-catenin and NF-κB pathways

Fig. 1

Characterization of hsa_circ_0005243 in GDM. a, b Relative expression of hsa_circ_0005243 was determined by qRT-PCR in placenta tissues (a) and plasma (b) of GDM patients and normal controls. c ROC curve analysis was used to assess the diagnostic value of hsa_circ_0005243. d hsa_circ_0005243 is generated from the back-splicing of exons 2, 3, and 4 of the TMEM184B gene. e Sanger sequence analysis was used to confirm the splicing site. f qRT-PCR analysis of hsa_circ_0005243 and the linear TMEM184B mRNA after treatment with or without RNase R in HTR-8/SVneo cells

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