Fig. 1

Individual differences in fibroids volume before and after UPA treatment. UPA treatment led to a mean reduction in volume of the myoma impacting the cavity of 41% ± 13.37. The volume before treatment was 399.17 ± 285.20 ml and become 257.02 ± 203.83 after UPA cycles. The volume of myoma nodule was calculated as 1/6 π × L1 × L2 × L3 where L1, L2, and L3 are the three diameters of the nodule that are at right angles to each other. Individual differences in fibroids volume after treatment and the percentage of volume reduction for each patients were reported. The percentage of reduction was always significant. Only one patient did not respond to UPA treatment and showed a volume augmentation of 9.2%