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Table 3 Univariate and multivariate logistic regression model about NC, HRT and OI protocols

From: Increased risk of maternal and neonatal complications in hormone replacement therapy cycles in frozen embryo transfer

 Crude OR (95% Cl)P-valueAdjusted OR (95% Cl)P-value
HDP
 NC1 1 
 HRT2.36 (1.86–2.99)< 0.001*2.00 (1.54–2.60)< 0.001*
 OI1.34 (0.86–2.07)0.1931.02 (0.62–1.65)0.853
GDM
 NC1 1 
 HRT1.25 (0.99–1.58)0.0611.10 (0.84–1.45)0.470
 OI1.48 (1.04–2.10)0.028*1.49 (0.97–2.19)0.056
Placenta previa
 NC1 1 
 HRT1.48 (0.90–2.42)0.1221.52 (0.88–2.64)0.133
 OI1.17 (0.50–2.75)0.7201.35 (0.55–3.27)0.514
Oligohydramnios
 NC1 1 
 HRT0.80 (0.47–1.37)0.4190.70 (0.40–1.24)0.225
 OI1.36 (0.67–2.75)0.3991.06 (0.49–2.29)0.887
PTB
 NC1 1 
 HRT1.84 (1.47–2.30)< 0.001*1.78 (1.39–2.28)< 0.001*
 OI1.76 (1.24–2.50)0.002*1.51 (1.02–2.23)0.041*
LBW
 NC1 1 
 HRT1.67 (1.25–2.23)0.001*1.49 (1.09–2.06)0.014*
 OI1.35 (0.83–2.20)0.2311.17 (0.70–1.96)0.547
SGA
 NC1 1 
 HRT0.83 (0.60–1.15)0.2710.85 (0.60–1.21)0.370
 OI1.46 (0.96–2.24)0.0781.47 (0.94–2.31)0.092
LGA
 NC1 1 
 HRT1.16 (1.02–1.33)0.021*1.15 (0.99–1.33)0.058
 OI0.93 (0.75–1.16)0.5050.98 (0.77–1.24)0.842
  1. NC natural cycle, HRT hormone replacement therapy, OI ovulation induction, OR odds ratio, CI confidence interval, HDP hypertensive disorders of pregnancy, GDM gestational diabetes mellitus, PTB preterm birth, LBW low birth weight, SGA small for gestational age, LGA large for gestational age
  2. Adjustment included age, body mass index, irregular menstruation, donor sperm using, FET cycle number, number of transferred embryos, vanishing twin gestation, preconceptional fasting glucose, systolic pressure, diastolic pressure, endometrial thickness, antral follicle count, testosterone level, anti-Müllerian hormone
  3. *There were significant differences between groups