Fig. 2
From: Low doses of Bisphenol S affect post-translational modifications of sperm proteins in male mice
Stereological and histopathological analyses of mouse testis in different treatment groups. (a) Fluctuations in the total testis volume (μm3) in experimental groups; (b) volume of germinal epithelium (μm3); and (c, c’) stage of spermatogenesis (%) were recorded. Histopathological manifestations were tracked as follows: (d) portion of seminiferous tubule profiles containing an abnormality (%), including (e) tubes with vacuolisation (%), (f) tubes carrying large multinuclear germ cells (%), (g) atypical residual bodies (%), and/or (h) maturation depletion (%). (d’) Representative images of healthy germ epithelium and (e’–h’) individual abnormalities, respectively, are shown and indicated with arrowheads. Data are expressed as medians and 5–95% percentiles of six animals per experimental group. Kruskal-Wallis tests, followed by Dunn’s multiple comparison tests, were performed, and statistical significance is indicated (*p < 0.05, **p < 0.01). VC: vehicle control, BPS1–3: increasing doses of bisphenol S