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Table 3 Characteristics of patients and blastocyst morphology grouped by chromosome karyotype of miscarried conceptus

From: Association between the quality of inner cell mass and first trimester miscarriage after single blastocyst transfer

Variable

Euploidy (n = 91)

Aneuploidy (n = 83)

P value

Maternal age at oocyte retrieval, y

28.2 ± 3.2

29.0 ± 3.1

0.088

Body mass index (BMI), kg/m2

23.4 ± 2.9

22.5 ± 3.3

0.065

Paternal age, y

29.4 ± 3.5

30.2 ± 3.6

0.142

Infertility diagnosis, n (%)

  

0.611

 Tubal factor

23 (25.3)

23 (27.7)

 

 Ovulatory disfunction

22 (24.2)

13 (15.7)

 

 Diminished ovarian reserve

1 (1.1)

2 (2.4)

 

 Male factor

22 (24.2)

19 (22.9)

 

 Unknown factor

23 (25.3)

26 (31.3)

 

Fertilization method, n (%)

  

0.207

 IVF

60 (65.9)

62 (74.7)

 

 ICSI

31 (34.1)

21 (25.3)

 

Cycle type, n (%)

  

0.074

 Fresh

36 (39.6)

45 (54.2)

 

 Frozen

55 (60.4)

38 (45.8)

 

Development days, n (%)

  

0.575

 Day 5

75 (82.4)

71 (85.5)

 

 Day 6

16 (17.6)

12 (14.5)

 

Expansion degree, n (%)

  

0.709

 1

1 (1.1)

0

 

 2

2 (2.2)

1 (1.2)

 

 3

21 (23.1)

23 (27.7)

 

 4

62 (68.1)

57 (68.7)

 

 5

4 (4.4)

2 (2.4)

 

 6

1 (1.1)

0

 

ICM grade a, n (%)

  

0.005

 A

24 (26.4)

39 (47.0)

 

 B

67 (73.6)

44 (53.0)

 

TE grade, n (%)

  

0.346

 A

14 (15.4)

12 (14.5)

 

 B

49 (53.8)

53 (63.9)

 

 C

28 (30.8)

18 (21.7)

 
  1. Values are presented as means ± SD or frequency (percentage)
  2. a Univariable logistic analysis for ICM grade B: euploid miscarriage versus aneuploid miscarriage, OR (95% CI), 2.474 (1.311–4.669), P = 0.005