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Table 3 Characteristics of patients and blastocyst morphology grouped by chromosome karyotype of miscarried conceptus

From: Association between the quality of inner cell mass and first trimester miscarriage after single blastocyst transfer

VariableEuploidy (n = 91)Aneuploidy (n = 83)P value
Maternal age at oocyte retrieval, y28.2 ± 3.229.0 ± 3.10.088
Body mass index (BMI), kg/m223.4 ± 2.922.5 ± 3.30.065
Paternal age, y29.4 ± 3.530.2 ± 3.60.142
Infertility diagnosis, n (%)  0.611
 Tubal factor23 (25.3)23 (27.7) 
 Ovulatory disfunction22 (24.2)13 (15.7) 
 Diminished ovarian reserve1 (1.1)2 (2.4) 
 Male factor22 (24.2)19 (22.9) 
 Unknown factor23 (25.3)26 (31.3) 
Fertilization method, n (%)  0.207
 IVF60 (65.9)62 (74.7) 
 ICSI31 (34.1)21 (25.3) 
Cycle type, n (%)  0.074
 Fresh36 (39.6)45 (54.2) 
 Frozen55 (60.4)38 (45.8) 
Development days, n (%)  0.575
 Day 575 (82.4)71 (85.5) 
 Day 616 (17.6)12 (14.5) 
Expansion degree, n (%)  0.709
 11 (1.1)0 
 22 (2.2)1 (1.2) 
 321 (23.1)23 (27.7) 
 462 (68.1)57 (68.7) 
 54 (4.4)2 (2.4) 
 61 (1.1)0 
ICM grade a, n (%)  0.005
 A24 (26.4)39 (47.0) 
 B67 (73.6)44 (53.0) 
TE grade, n (%)  0.346
 A14 (15.4)12 (14.5) 
 B49 (53.8)53 (63.9) 
 C28 (30.8)18 (21.7) 
  1. Values are presented as means ± SD or frequency (percentage)
  2. a Univariable logistic analysis for ICM grade B: euploid miscarriage versus aneuploid miscarriage, OR (95% CI), 2.474 (1.311–4.669), P = 0.005