Table 1 Characteristics of patients and blastocyst morphology for all clinical pregnancy cycles
Variable | Miscarriage (n = 354) | No miscarriage (n = 2519) | P value |
|---|---|---|---|
Maternal age at oocyte retrieval, y | 28.6 ± 3.1 | 28.2 ± 3.0 | 0.006 |
Prior gravidity | 0.8 ± 1.0 | 0.8 ± 1.0 | 0.283 |
Prior parity | 0.2 ± 0.4 | 0.2 ± 0.5 | 0.692 |
Body mass index (BMI), kg/m2 | 23.2 ± 3.4 | 23.0 ± 5.1 | 0.180 |
Basal FSH, mIU/mL | 6.3 ± 1.8 | 6.2 ± 1.6 | 0.359 |
Paternal age, y | 30.0 ± 3.7 | 29.4 ± 3.5 | 0.007 |
Endometrial thickness, mm | 11.2 ± 2.5 | 11.7 ± 2.6 | 0.001 |
Infertility diagnosis, n (%) | Â | Â | 0.310 |
 Tubal factor | 117 (33.1) | 954 (37.9) |  |
 Ovulatory disfunction | 56 (15.8) | 316 (12.5) |  |
 Diminished ovarian reserve | 8 (2.3) | 51 (2.0) |  |
 Male factor | 81 (22.9) | 547 (21.7) |  |
 Unknown factor | 92 (26.0) | 651 (25.8) |  |
Fertilization method, n (%) | Â | Â | 0.392 |
 IVF | 257 (72.6) | 1773 (70.4) |  |
 ICSI | 97 (27.4) | 746 (29.6) |  |
Cycle type, n (%) |  |  | < 0.001 |
 Fresh | 153 (43.2) | 1499 (59.5) |  |
 Frozen | 201 (56.8) | 1020 (40.5) |  |
Development days of blastocyst, n (%) |  |  | < 0.001 |
 Day 5 | 292 (82.5) | 2288 (90.8) |  |
 Day 6 | 62 (17.5) | 231 (9.2) |  |
Expansion degree, n (%) | Â | Â | 0.496 |
 1 | 3 (0.8) | 26 (1.0) |  |
 2 | 21 (5.9) | 101 (4.0) |  |
 3 | 92 (26.0) | 699 (27.7) |  |
 4 | 227 (64.1) | 1586 (63.0) |  |
 5 | 9 (2.5) | 93 (3.7) |  |
 6 | 2 (0.6) | 14 (0.6) |  |
ICM grade, n (%) | Â | Â | 0.404 |
 A | 124 (35.0) | 940 (37.3) |  |
 B | 230 (65.0) | 1579 (62.7) |  |
TE grade, n (%) | Â | Â | 0.012 |
 A | 46 (13.0) | 423 (16.8) |  |
 B | 201 (56.8) | 1503 (59.7) |  |
 C | 107 (30.2) | 593 (23.5) |  |