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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome

Fig. 2

Expression of circadian clock genes and insulin pathway genes in the liver tissue of control and DHEA rats. aBmal1, Clock, Per1, Per2, Cry1, and Cry2 mRNA expressions in the liver of control and DHEA rats. b P-AKT, T-AKT, and BMAL1 protein expressions in the liver of control and DHEA rats. Left, a representative western blot is shown. Middle, the immunoreactive bands for BMAL1 were quantified densitometrically. Right, the immunoreactive bands for AKT phosphorylation were quantified densitometrically. c mRNA expression of insulin pathway-associated genes including Sirt1, Nampt, Glut4, and Pparg in the liver of control and DHEA rats. N = 6 per time point and N = 30 for each group in total. * p < 0.05, ** p < 0.01

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