High serum Antimullerian hormone levels are associated with lower live birth rates in women with polycystic ovarian syndrome undergoing assisted reproductive technology

Table 2 Cycle characteristics and ART outcomes

Variable		Serum AMH (ng/ml)
Variable	Low, < 3.32 n = 46	Average, 3.32–8.27 n = 92	High, > 8.27 n = 46	p-value Low vs. High	p-value Low vs. Average	p-value Average vs. High
GnRH Antagonist (%)	81.2	72.3	68.8	NS	NS	NS
GnRH agonist (%)	18.8	27.7	31.2	NS	NS	NS
Total gonadotropin dose (IU)	3316 ± 1288	2587 ± 1071	2252 ± 842	< 0.01	< 0.05	NS
E2 (pg/ml) on day of hCG	2656 ± 964	2521 ± 880	2806 ± 1087	NS	NS	NS
Number of oocytes retrieved	11.8 ± 6.3	13.4 ± 6.2	14.6 ± 8.0	NS	NS	NS
Number of fertilizations	8.8 ± 4.9	8.6 ± 4.1	9.5 ± 5.6	NS	NS	NS
Number of embryos cryopreserved	1.8 ± 2.7	2.8 ± 2.6	3.2 ± 2.8	NS	NS	NS
Day 5 transfer (%)	78.1	70.8	71.1	NS	NS	NS
Number of embryos transferred	2.2 ± 0.7	1.9 ± 0.7	1.9 ± 0.8	NS	NS	NS
Fertilization rate (%)	70.4	64.2	66.5	NS	NS	NS
Implantation rate (%)	47.1	40.6	35.3	NS	NS	NS
Clinical pregnancy rate (%)	69.6	53.2	52.2	NS	NS	NS
Live birth rate (%)	65.2	46.7	43.5	< 0.05	< 0.05	NS
Multiple pregnancy rate (%)	26.0	21.7	13.0	NS	NS	NS
OHSS (%)	8.7	4.3	8.7	NS	NS	NS

GnRH, gonadotropin releasing hormone; OHSS, ovarian hyperstimulation syndrome; hCG, human chorionic gonadotropin; E2, estradiol;

ISSN: 1477-7827