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Table 2 Comparison of clinical outcomes from LPOS and FPOS protocols

From: Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: results of a randomized controlled trial

 

LPOS

FPOS

p value

Mean Difference (95% CI)

Oocytes MII, mean ± SD

2.1 ± 2.0

2.6 ± 2.2

0.31a

0.57 (− 1.67, 1.14)

COCs, mean ± SD

2.7 ± 2.5

3.1 ± 2.1

0.44a

0.47 (− 1.66, 0.73)

Length of stimulation, mean ± SD, days

8.4 ± 2.8

8.2 ± 4.1

0.69a

0.2 (− 2.5, 2.1)

Total FSH dose, mean ± SD, IU

2505 ± 913

2445 ± 690

0.76a

65 (353.5, 483.5)

Cancellation rate, %

20

10

0.09b

1.6 (0.61, 4.15)

Survival rate, %

94.9

83.6

0.09 a

1.01 (0.98, 1.04)

Fertilization rate, %

68.9

65.7

0.78a

1.01 (0.99, 1.04)

OSI

0.96

0.57

0.04

0.39 (0.02, 0.75)

  1. COCs cumulus-oocyte complexes, FSH follicle-stimulating hormone, OSI Ovarian Sensitivity Index, MII metaphase II, SD standard deviation
  2. aCalculated using student t-test
  3. bCalculated using χ2 test