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Table 3 Neonatal outcomes of FETs between immediate and delayed groups stratified by COS protocol

From: Delayed frozen embryo transfer failed to improve live birth rate and neonatal outcomes in patients requiring whole embryo freezing

 

GnRHa protocol

GnRHant protocol

Immediate FET

(n = 1585)

Delayed FET

(n = 1525)

P value

Immediate FET

(n = 778)

Delayed FET

(n = 516)

P value

Preterm birth (<37 weeks)

24.4 (189/774)

26.4 (197/745)

0.365

23.1 (92/399)

19.4 (51/263)

0.262

Still birth

0.4 (3/774)

0.1 (1/745)

0.625

0.3 (1/399)

0 (0/263)

1.000

Gestational age (weeks)

37.41 ± 2.44

37.46 ± 2.29

0.731

37.45 ± 2.45

37.57 ± 2.27

0.515

Birth height (mm)

49.04 ± 2.68

48.91 ± 2.36

0.356

48.37 ± 3.27

48.58 ± 2.84

0.179

Birth weight (kg)

3.00 ± 0.62

2.99 ± 1.15

0.891

2.93 ± 0.64

2.91 ± 0.60

0.548

Low birth weight (<2500 g)

22.8 (225/988)

25.1 (247/983)

0.221

21.4 (106/496)

19.7 (66/335)

0.560

Very low birth weight (<1500 g)

1.6 (16/988)

1.8 (18/983)

0.718

2.2 (11/496)

2.4 (8/335)

0.872

Congenital anomalies

1.0 (10/988)

0.3 (3/983)

0.053

2.2 (11/496)

1.2 (4/335)

0.277

Sex ratio (male/female)

1.17 (532/456)

1.17 (529/454)

0.989

1.28 (278/218)

1.31 (190/145)

0.849