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Table 2 Stimulation characteristics of the women with PCOS in the three groups

From: Transvaginal ovarian drilling followed by controlled ovarian stimulation from the next day improves ovarian response for the poor responders with polycystic ovary syndrome during IVF treatment: a pilot study

Variable

Poor responders (n = 7) (after TVOD)

High responders (n = 14)

Normal responders (n = 14)

P value

Stimulation duration (days)

8.00 ± 1.73

9.14 ± 0.53

9.21 ± 1.12

0.050

Total gonadotrophin used (IU)

2592.86 ± 430.53

2247.64 ± 1448.42

2140.18 ± 645.08

0.635

No. of oocytes retrieved

11.14 ± 5.55a

20.21 ± 4.04

12.79 ± 3.09a

< 0.001

Fertilization rate (%)

60/78 (76.9%)

214/283 (75.6%)

145/179 (81.0%)

0.396

No. of available embryos

4.43 ± 2.37

7.43 ± 3.57

4.64 ± 1.95

0.057

Available embryo rate (%)

31/60 (51.7%)

104/214 (48.6%)

65/145 (44.8%)

0.629

Endometrial thickness on the hCG day (cm)

1.06 ± 0.22

0.99 ± 0.17

0.99 ± 0.18

0.721

Grade A rate of endometrial morphology (%)

5/7 (71.4%)

11/14 (78.6%)

8/14 (57.1%)

0.525

Size of left ovary (2 h after oocyte retrieval, cm3)

81.64 ± 27.82a

184.57 ± 47.89

80.94 ± 12.83a

< 0.001

Size of right ovary (2 h after oocyte retrieval, cm3)

91.44 ± 29.37a

186.10 ± 42.54

87.12 ± 18.33a

< 0.001

Size of left ovary (7 days after oocyte retrieval, cm3)

78.97 ± 28.90a

180.51 ± 34.33

71.10 ± 17.17a

< 0.001

Size of right ovary (7 days after oocyte retrieval, cm3)

81.31 ± 39.43a

173.67 ± 34.67

76.31 ± 17.64a

< 0.001

Severe OHSS rate (%)

0/7 (0%)

1/14 (7.1%)

0/14 (0%)

1.000

No. of FET cycles

8

21

23

Total number of embryo transfer

15

31

36

Cumulative implantation rate (%)

9/15 (60.0%)

15/31 (48.4%)

14/36 (38.9%)

0.371

Cumulative clinical pregnancy rate (%)

8/8 (100.0%)

12/21 (57.1%)

13/23 (56.5%)

0.062

Cumulative abortion rate (%)

1/8 (12.5%)

1/12 (8.3%)

0/13 (0.0%)

0.508

  1. Data are presented as mean ± SD for quantitative variables and frequency for qualitative variables. Size of the ovary was estimated using the equation: π/6 (transverse diameter) × (anteroposterior diameter) × (longitudinal diameter). Statistical significance was defined as P < 0.05. “a” refers to P < 0.01, when compared with high responders