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Table 2 Stimulation characteristics of the women with PCOS in the three groups

From: Transvaginal ovarian drilling followed by controlled ovarian stimulation from the next day improves ovarian response for the poor responders with polycystic ovary syndrome during IVF treatment: a pilot study

VariablePoor responders (n = 7) (after TVOD)High responders (n = 14)Normal responders (n = 14)P value
Stimulation duration (days)8.00 ± 1.739.14 ± 0.539.21 ± 1.120.050
Total gonadotrophin used (IU)2592.86 ± 430.532247.64 ± 1448.422140.18 ± 645.080.635
No. of oocytes retrieved11.14 ± 5.55a20.21 ± 4.0412.79 ± 3.09a< 0.001
Fertilization rate (%)60/78 (76.9%)214/283 (75.6%)145/179 (81.0%)0.396
No. of available embryos4.43 ± 2.377.43 ± 3.574.64 ± 1.950.057
Available embryo rate (%)31/60 (51.7%)104/214 (48.6%)65/145 (44.8%)0.629
Endometrial thickness on the hCG day (cm)1.06 ± 0.220.99 ± 0.170.99 ± 0.180.721
Grade A rate of endometrial morphology (%)5/7 (71.4%)11/14 (78.6%)8/14 (57.1%)0.525
Size of left ovary (2 h after oocyte retrieval, cm3)81.64 ± 27.82a184.57 ± 47.8980.94 ± 12.83a< 0.001
Size of right ovary (2 h after oocyte retrieval, cm3)91.44 ± 29.37a186.10 ± 42.5487.12 ± 18.33a< 0.001
Size of left ovary (7 days after oocyte retrieval, cm3)78.97 ± 28.90a180.51 ± 34.3371.10 ± 17.17a< 0.001
Size of right ovary (7 days after oocyte retrieval, cm3)81.31 ± 39.43a173.67 ± 34.6776.31 ± 17.64a< 0.001
Severe OHSS rate (%)0/7 (0%)1/14 (7.1%)0/14 (0%)1.000
No. of FET cycles82123
Total number of embryo transfer153136
Cumulative implantation rate (%)9/15 (60.0%)15/31 (48.4%)14/36 (38.9%)0.371
Cumulative clinical pregnancy rate (%)8/8 (100.0%)12/21 (57.1%)13/23 (56.5%)0.062
Cumulative abortion rate (%)1/8 (12.5%)1/12 (8.3%)0/13 (0.0%)0.508
  1. Data are presented as mean ± SD for quantitative variables and frequency for qualitative variables. Size of the ovary was estimated using the equation: π/6 (transverse diameter) × (anteroposterior diameter) × (longitudinal diameter). Statistical significance was defined as P < 0.05. “a” refers to P < 0.01, when compared with high responders