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Table 1 Risky and protective lifestyles and their effects on male and female sexuality

From: Lifestyles and sexuality in men and women: the gender perspective in sexual medicine

Factor

Effects on male sexuality

Effects on female sexuality

Obesity

Loss of libido [8]

Risk of ED > 30% with BMI > 28.7 [13]

Arousal problems, Coital pain and Sexual dissatisfaction [8]

More sexual complaints in women seeking bariatric surgery [22]

Higher risk for postmenopausal breast cancer [27, 28]

Loss of weightand Diet

10% weight loss related with increased insulin sensitivity, plasma testosterone levels, erectile function and desire both in diabetics and non-diabetics [52]

Weight loss induced by bariatric surgery improve erectile functions and testosterone levels [53]

Mediterranean diet improves IIEF scores after 2-years [54]

Adherence to Mediterranean diet improve BMI, waist circumference, waist-to-hip ratio, mood symptoms, weight and metabolic syndrome [55]

Higher frequency of sexual intercourses in women who better comply to Mediterranean diet [55]

Physical Activity

Protective effects against ED in men with diabetes [34]

Increase of NO production and decrease of oxidative stress [14]

Benefits on self-esteem and mental health [36, 41]

Improvement of IIEF-5 score after 3 months of physical exercise [38]

Augmented improvement of ED symptoms in association with PDE5i treatment [39]

Sedentary life increase PE symptoms [41]

Protective effects against sexual dysfunction in women with diabetes [35]

Benefits on self-esteem and mental health [36, 52]

Improvement of menopause symptoms, mood, anxiety and musculoskeletal problems [47,48,49]

Keeping good sexual quality of life in postmenopausal women who do regular physical activity [48]

Regual physical exercises prevent the development of sexual dysfunction [51]

Smoking

Quit with smoking improve erectile function by 25% after 1 year [61]

>  50% odds to develop ED in smokers and 30% in ex-smokers [60]

30% decrease of genital stimulation due to nicotine acute intake [62]

Delayed orgasm and low vaginal lubrication [10, 64, 65]

Alcohol abuse

Lower likelihood of developing ED between non-habitual drinkers compared to binge-drinkers [68, 71]

Low sexual desire, inability to reach orgasm or unsatisfactory orgasm in women with an alcohol dependence [68, 73]

Marijuana

Physiological decline of testosterone levels [81]

It gives major facilitatory effects [81]

Cocaine

Depressive effect on sexual activity and progressive inability to reach orgasm in the long term [82, 83]

Loss of sexual desire, ED symptoms, inhibition of ejaculation and reduction in sexual performance [83, 85]

Loss of sexual activity [84]

Amphetamine

Decrease in sexual desire, inhibition of orgasm and a reduction of sexual satisfaction [87]

 

Heroin

At early stages, it improves sexual inadequacy, sexual performance and ejaculatory control [88]

Heroin dependence produces loss of libido and ED [90]

Heroin dependence produces delayed ejaculation or inability to reach it [91]

At early stages, it reduces anxiety and coital pain, due to a relaxation of pelvic floor muscles and higher lubrication [88]

Ecstasy

At early stages, it reduces sexual inhibition [92]

Long-term use reduces sexual desire and penile erection [93]

At early stages, it maximized sexual experience and orgasm [77]

Long-term use reduces vaginal lubrication and ability to reach satisfying orgasm [93]

Chronic stress

PDE5i treatment combined with stress management techniques reduces cortisol levels and improves IIEF scores [113]

Chronic stress is related to lower levels of sexual arousal both in hormonal factors (cortisol) and psychological factors (attention to visual sexual stimuli) [114]