Fig. 4From: Ovulatory signals alter granulosa cell behavior through YAP1 signalingDosage-dependent effect of verteporfin on the steroidogenesis of COCs. Fold change of steroidogenic transcripts (Star, Cyp11a1, Hsd3β2) in COCs treated with verteporfin (200 nM or 1 μM) for 16 h, N = 3–9 and media progesterone (pg/complex) in conditioned media from COC (2 COCs/μl) treated with medium only (control) or verteporfin (1 μM) for 16 h, N = 6. Values are mean ± SEM. A,B indicates significant differences by one-way ANOVA followed by Tukey’s post-hoc test, P < 0.05. *Indicates significant differences from control by Student’s T-test, P < 0.05Back to article page