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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Ovulatory signals alter granulosa cell behavior through YAP1 signaling

Fig. 4

Dosage-dependent effect of verteporfin on the steroidogenesis of COCs. Fold change of steroidogenic transcripts (Star, Cyp11a1, Hsd3β2) in COCs treated with verteporfin (200 nM or 1 μM) for 16 h, N = 3–9 and media progesterone (pg/complex) in conditioned media from COC (2 COCs/μl) treated with medium only (control) or verteporfin (1 μM) for 16 h, N = 6. Values are mean ± SEM. A,B indicates significant differences by one-way ANOVA followed by Tukey’s post-hoc test, P < 0.05. *Indicates significant differences from control by Student’s T-test, P < 0.05

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