Fig. 1
From: Ovulatory signals alter granulosa cell behavior through YAP1 signaling
Effect of oocytes and pSMAD2/3 inhibitor on the abundance of Hippo transcripts in cumulus cells a. Abundance of Lats1, Lats2, Sav1 and Mob1b transcripts in cumulus cells from intact cumulus-oocyte complexes (COC), oocytectomized COC (OOX) and OOX co-cultured with fully-grown oocytes (OO) for 20 h. b. Abundance of Lats1, Lats2, Sav1 and Mob1b transcripts in COCs cultured alone (control) or with the pSMAD2/3 inhibitor, SB431542 (10 μM) for 16 h. Values are mean ± SEM, N = 4–5. A,B indicates significant differences by one-way ANOVA followed by Tukey’s post-hoc test, P < 0.05. *Indicates significant differences from control by Student’s T-test, P < 0.05