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Table 1 Clinical and pretreatment parameters, follicular fluid and serum concentrations of hormones in 165 patients undergoing ovarian stimulation

From: Serum and follicular fluid thyroid hormone levels and assisted reproductive technology outcomes

VariablesSuccessful
Pregnancy
(N = 72)
Implantation
Failure
(N = 93)
P value
Clinical and treatment parameters
 Age (yrs)31 (28,34)34 (28,36)NS
 BMI (kg/m2)22.5 (20.6,25.2)20.8 (18.9,22.6)≤0.001
 Basal FSH3.63 (1.95,6.01)4.22 (1.79,7.11)NS
 AMH (ng/ml)3.56 (1.78,3.91)3.46 (2.25,4.13)NS
 Oocytes (total)13.5 (8.8,16.8)10 (7,14)0.007
 Oocyte (MII)
 Fertilization rate,%
10.5 (5.5,15)
65.9%
8 (6,10)
56.6%
0.002
≤0.001
 Etiology of infertility(%)  0.395
 Female infertility75%77.4% 
 Both male and female infertility16.7%9.7% 
 Infertility of unknown cause8.3%12.9% 
 Cleavage rate,%98%99.5%NS
Serum (day HCG) hormone levels
 TSH (mIU/l)1.86 (1.27,3.08)1.95 (1.54,2.95)NS
 T4(nmol/l)121.9 (104.8,140.8)114.1 (98.6,130.6)0.026
 T3(nmol/l)1.98 (1.74,2.22)1.98 (1.75,2.13)NS
 fT4(pmol/l)19.0 (17.7,21.8)18.6 (17.0,20.1)0.026
 fT3(pmol/l)4.75 (4.25,4.93)4.5 (4.08,4.8)NS
 TPO Ab (IU/ml)15.1 (9.17,23.22)15.5 (8.94,17.32)NS
 TG Ab (IU/ml)16.6 (13.86,22.2)14.4 (13.3,19.9)NS
 T4/T362.5 (55.7,66.2)59.4 (53.4,64.9)0.029
Follicular fluid hormone levels
 TSH (mIU/l)2.12 (1.41,3.57)2.41 (2.03.3.23)NS
 T4(nmol/l)112.3 (93.7124.5)102.6 (88.6116.8)NS
 T3(nmol/l)2.07 (1.88.2.22)1.98 (1.75,2.13)NS
 fT4(pmol/l)19.0 (17.5,21.3)18.1 (16.8,19.9)0.009
 fT3(pmol/l)4.67 (4.33,5.0)4.19 (4.20,4.88)NS
 TPO Ab (IU/ml)8.4 (5.0,13.9)10.1 (5.0,12.7)NS
 TG Ab (IU/ml)17.5 (13.98,24.38)17.6 (14.9,20.3)NS
 T4/T352.6 (46.4,57.3)50.0 (43.7,53.1)0.004
  1. Note: Values are Mean ± SD, median and interquartile range, or n (%) as indicated
  2. NS nonsignificant,which means P ≥ 0.05
  3. FF follicular fluid, BMI body mass index, AMH anti-Mullerian hormone