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Table 2 Comparison of clinical parameters between parturients with spontaneous and ART conception stratified based on treatment modalities

From: Assisted conception as a potential prognostic factor predicting insulin therapy in pregnancies complicated by gestational diabetes mellitus

Variables

SC (n = 136)

ART (n = 100)

OR3 (CI 5%) c

P-value

MNT (n = 102)

MNI-IT (n = 34)

OR1 (CI 95%) a

P-value

MNT (n = 60)

MNT-IT (n = 40)

OR2 (CI 95%) b

P-value

Maternal age (Years, Mean ± SE)

30.64 ± 0.53

34.38 ± 0.73

1.17 (1.07–1.28)

0.001*

32.05 ± 0.77

32.65 ± 0.62

1.02 (0.95–1.10)

0.576

1.94 (1.10–3.41)

0.023*

Maternal age ≥ 35 years,n (%)

26 (25.5)

16 (47.0)

2.6 (1.16–5.82)

0.018*

19 (31.7)

15 (37.5)

1.29 (0.55–2.99)

0.546

1.87 (1.05–3.33)

0.032*

Parity (n = 0), n (%)

46 (45.1)

10 (29.4)

11.97 (0.86–4.54)

0.108

50 (83.3)

37 (92.5)

0.41 (0.10–1.58)

0.182

0.84 (0.47–1.47)

0.535

Family history of DM (Yes, n %)

35 (34.3)

17 (50.0)

1.91 (0.87–4.20)

0.103

20 (33.3)

22 (55.0)

2.44 (1.07–5.56)

0.033*

2.17(1.24–3.79)

0.007*

Systolic blood pressure (Mean ± SE)

106.37 ± 1.01

109.11 ± 0.72

1.03 (0.99–1.07)

0.176

107.25 ± 1.17

106.0 ± 1.82

0.99 (0.95–1.03)

0.542

1.01 (0.98–1.03)

0.424

Diastolic blood pressure (Mean ± SE)

68.22 ± 0.83

69.71 ± 1.42

1.02 (0.97–1.07)

0.367

66.83 ± 0.98

67.0 ± 1.25

1.00 (0.96–1.06)

0.915

1.0 (0.97–1.04)

0.574

Pre-pregnancy BMI (Mean ± SE)

25.44 ± 0.49

27.31 ± 0.81

1.08 (1.00–1.17)

0.059

27.22 ± 0.46

27.52 ± 0.76

1.01 (0.95–1.12)

0.726

1.94 (1.09–3.45)

0.022*

Pre-pregnancy BMI ≥25 (kg/m2), n (%)

49(49.1)

23 (71.9)

2.65 (1.12–6.31)

0.024*

43 (71.7)

29 (72.5)

1.04 (0.43–2.55)

0.928

1.92 (1.05–3.51)

0.034*

History of spontaneous abortion, n (%)

26 (26.0)

13 (38.2)

1.76 (0.77–4.02)

0.175

16 (26.7)

16 (40)

1.83 (0.78–4.30)

0.161

1.90 (1.12–3.23)

0.018*

History of GDM, (Yes, n %)

8 (7.8)

10 (29.4)

4.90 (1.74–13.74)

0.001*

1 (1.7)

0 (0)

–

1

2.66 (1.03–6.84)

0.043*

History of macrosomia, (Yes, n %)

4 (3.9)

2 (5.8)

1.53 (0.27–8.76)

0.630

1 (1.7)

0 (0)

0.87 (0.16–4.60)

0.872

0.66 (0.13–3.35)

0.619

  1. CI Confidence Interval, GDM gestational diabetes mellitus, SC Spontaneous Conception, ART Assisted Reproductive Technology, MNT Medical Nutrition Therapy, MNT-IT Medical Nutrition Therapy plus Insulin Therapy
  2. *P < 0.05 was considered statistically significant
  3. a OR1; Fitting GDM treatment modality as the outcome of the univariate regression models. The reference group was the MNT subgroup compared to the MNT-IT in SC group
  4. b OR2; Fitting GDM treatment modality as the outcome of the univariate regression models; The reference group was the MNT subgroup compared to the MNT-IT in ART group
  5. c OR3; Fitting GDM treatment modality as the outcome of the univariate regression models; The reference group was the MNT subgroup compared to the MNT-IT in the total population
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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