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Table 2 Comparison of clinical parameters between parturients with spontaneous and ART conception stratified based on treatment modalities

From: Assisted conception as a potential prognostic factor predicting insulin therapy in pregnancies complicated by gestational diabetes mellitus

Variables SC (n = 136) ART (n = 100) OR3 (CI 5%) c P-value
MNT (n = 102) MNI-IT (n = 34) OR1 (CI 95%) a P-value MNT (n = 60) MNT-IT (n = 40) OR2 (CI 95%) b P-value
Maternal age (Years, Mean ± SE) 30.64 ± 0.53 34.38 ± 0.73 1.17 (1.07–1.28) 0.001* 32.05 ± 0.77 32.65 ± 0.62 1.02 (0.95–1.10) 0.576 1.94 (1.10–3.41) 0.023*
Maternal age ≥ 35 years,n (%) 26 (25.5) 16 (47.0) 2.6 (1.16–5.82) 0.018* 19 (31.7) 15 (37.5) 1.29 (0.55–2.99) 0.546 1.87 (1.05–3.33) 0.032*
Parity (n = 0), n (%) 46 (45.1) 10 (29.4) 11.97 (0.86–4.54) 0.108 50 (83.3) 37 (92.5) 0.41 (0.10–1.58) 0.182 0.84 (0.47–1.47) 0.535
Family history of DM (Yes, n %) 35 (34.3) 17 (50.0) 1.91 (0.87–4.20) 0.103 20 (33.3) 22 (55.0) 2.44 (1.07–5.56) 0.033* 2.17(1.24–3.79) 0.007*
Systolic blood pressure (Mean ± SE) 106.37 ± 1.01 109.11 ± 0.72 1.03 (0.99–1.07) 0.176 107.25 ± 1.17 106.0 ± 1.82 0.99 (0.95–1.03) 0.542 1.01 (0.98–1.03) 0.424
Diastolic blood pressure (Mean ± SE) 68.22 ± 0.83 69.71 ± 1.42 1.02 (0.97–1.07) 0.367 66.83 ± 0.98 67.0 ± 1.25 1.00 (0.96–1.06) 0.915 1.0 (0.97–1.04) 0.574
Pre-pregnancy BMI (Mean ± SE) 25.44 ± 0.49 27.31 ± 0.81 1.08 (1.00–1.17) 0.059 27.22 ± 0.46 27.52 ± 0.76 1.01 (0.95–1.12) 0.726 1.94 (1.09–3.45) 0.022*
Pre-pregnancy BMI ≥25 (kg/m2), n (%) 49(49.1) 23 (71.9) 2.65 (1.12–6.31) 0.024* 43 (71.7) 29 (72.5) 1.04 (0.43–2.55) 0.928 1.92 (1.05–3.51) 0.034*
History of spontaneous abortion, n (%) 26 (26.0) 13 (38.2) 1.76 (0.77–4.02) 0.175 16 (26.7) 16 (40) 1.83 (0.78–4.30) 0.161 1.90 (1.12–3.23) 0.018*
History of GDM, (Yes, n %) 8 (7.8) 10 (29.4) 4.90 (1.74–13.74) 0.001* 1 (1.7) 0 (0) 1 2.66 (1.03–6.84) 0.043*
History of macrosomia, (Yes, n %) 4 (3.9) 2 (5.8) 1.53 (0.27–8.76) 0.630 1 (1.7) 0 (0) 0.87 (0.16–4.60) 0.872 0.66 (0.13–3.35) 0.619
  1. CI Confidence Interval, GDM gestational diabetes mellitus, SC Spontaneous Conception, ART Assisted Reproductive Technology, MNT Medical Nutrition Therapy, MNT-IT Medical Nutrition Therapy plus Insulin Therapy
  2. *P < 0.05 was considered statistically significant
  3. a OR1; Fitting GDM treatment modality as the outcome of the univariate regression models. The reference group was the MNT subgroup compared to the MNT-IT in SC group
  4. b OR2; Fitting GDM treatment modality as the outcome of the univariate regression models; The reference group was the MNT subgroup compared to the MNT-IT in ART group
  5. c OR3; Fitting GDM treatment modality as the outcome of the univariate regression models; The reference group was the MNT subgroup compared to the MNT-IT in the total population