Fig. 4

AS-IV treatment inhibited NLRP3 inflammasome in the pancreas of GDM mice model. a Detection of inflammasome proteins expression (including IL-1β, Casp-1 p10, NLRP3, Pro-IL-1β, and Casp-1 p45) in the pancreas of pregnant wild mice or treated GDM mice on gestation day 14. β-actin was set as control protein. Relative expression of IL-1β (b), Casp-1 p10 (c), and NLRP3 (d) compared to control protein β-actin. Data was presented as mean ± SD. n = 8. * p < 0.05, ** p < 0.01, *** p < 0.005, vs vehicle-treated GDM mice