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Table 2 Clinical and biological outcomes

From: A monocentric analysis of the efficacy of extracellular cryoprotectants in unfrozen solutions for cleavage stage embryos

 

Kit 1

Kit 2

Kit 3

P value

N. of patients

288

966

418

 

Age of female partners (mean ± SD)

36.06 ± 3.73

35.76 ± 3.76

35.65 ± 4.04

0.329

Transferred embryos per patient (mean ± SD)

1.54 ± 1.15

1.77 ± 1.58

2.27 ± 1.80

< 0.001*

Survival rate of thawed embryos (%)

75.57

68.14

79.92

< 0.001*

Degeneration rate of blastomeres (%)

43.58

52.38

41.48

< 0.001*

FER rate (%)

86.45

83.38

91.54

< 0.001*

Implantation rate (%)

5.14

4.83

5.08

0.936

Clinical pregnancy rate per thawing cycles (%)

6.45

8.27

9.23

0.370

Clinical pregnancy rate per FER (%)

7.46

9.92

10.08

0.436

Abortion rate (%)

35

24.24

20.83

0.459

Delivery rate per total pregnancies (%)

44.83

37.76

49.33

0.246

Delivery rate per thawing cycle (%)

4.19

4.51

7.12

0.058

Live birth rate (%)

2.59

1.93

3.07

0.069

  1. *Significant (P < 0.05) difference between kit 1, kit 2 and kit 3. FER Frozen Embryo Replacement, SD Standard deviation