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Table 2 Clinical and biological outcomes

From: A monocentric analysis of the efficacy of extracellular cryoprotectants in unfrozen solutions for cleavage stage embryos

  Kit 1 Kit 2 Kit 3 P value
N. of patients 288 966 418  
Age of female partners (mean ± SD) 36.06 ± 3.73 35.76 ± 3.76 35.65 ± 4.04 0.329
Transferred embryos per patient (mean ± SD) 1.54 ± 1.15 1.77 ± 1.58 2.27 ± 1.80 < 0.001*
Survival rate of thawed embryos (%) 75.57 68.14 79.92 < 0.001*
Degeneration rate of blastomeres (%) 43.58 52.38 41.48 < 0.001*
FER rate (%) 86.45 83.38 91.54 < 0.001*
Implantation rate (%) 5.14 4.83 5.08 0.936
Clinical pregnancy rate per thawing cycles (%) 6.45 8.27 9.23 0.370
Clinical pregnancy rate per FER (%) 7.46 9.92 10.08 0.436
Abortion rate (%) 35 24.24 20.83 0.459
Delivery rate per total pregnancies (%) 44.83 37.76 49.33 0.246
Delivery rate per thawing cycle (%) 4.19 4.51 7.12 0.058
Live birth rate (%) 2.59 1.93 3.07 0.069
  1. *Significant (P < 0.05) difference between kit 1, kit 2 and kit 3. FER Frozen Embryo Replacement, SD Standard deviation