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Table 2 Number and percentage (%) of euploid and aneuploid blastocysts. Blastocysts were classified according to clinical indication for preimplantational genetic test for aneuploidies (PGT-A) and by genetic categories: euploids, whole-chromosome aneuploids and segmental aneuploids (with or without whole-chromosome aneuploidy associated). Data from blastocysts presenting only one segmental aneuploidy (without any additional whole-chromosome gain/loss) were classified as single segmental aneuploid (SSA)

From: Segmental aneuploidy in human blastocysts: a qualitative and quantitative overview

Clinical indication (n) Number of euploid blastocysts (n, %) Number of aneuploid blastocysts (n, %) with:
One or more whole-chromosome aneuploidies* Segmental aneuploidy
Without whole-chromosome aneuploidies associated With one or more whole-chromosome aneuploidies associated
One segmental aneuploidy (SSA) > 1 segmental aneuploidy One segmental Aneuploidy > 1 segmental aneuploidy
Recurrent miscarriage (453) 245 (54.1) a 169 (37.3) b 21 (4.6) 4 (0.9) 13 (2.9) 1 (0.2)
Advanced maternal age (1778) 623 (35.0) b 1011 (56.9) a 67 (3.8) 3 (0.2) 67 (3.8) 7 (0.4)
Prior chromosome pathology (208) 126 (60.6) a,c 66 (31.7) b,c 12 (5.8) 0 4 (1.9) 0
Male factor (457) 293 (64.1) c 127 (27.8) c 22 (4.8) 3 (0.6) 11 (2.4) 1 (0.2)
Implantation failure (570) 314 (55.1) a 207 (36.3) b 27 (4.7) 3 (0.5) 17 (2.9) 2 (0.3)
Sperm aneuploidy (99) 55 (55.6) a,c 30 (30.3) b,c 10 (10.1) 0 3 (3.0) 1 (1.0)
Total (3565) 1656 (46.4) 1610 (45.2) 159 (4.5) 13 (0.4) 115 (3.2) 12 (0.3)
  1. *Only whole-chromosome aneuploidy, no additional segmental aneuploidy
  2. a,b,c Different superscripts within a column indicate significantly statistical differences (P < 0.05)