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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model

Fig. 1

Complex II and I-mediated respiration are decreased in endometrium and endometriosis tissue from NHPs with endometriosis. a) Endometrium (EM, p = 0.003) and endometriosis (EMO, p = 0.04) tissue mitochondrial OCR was decreased at complex II-mediated basal respiration compared to normal endometrium (nEM). b) Complex II-mediated State 3 (p = 0.02), c) State 4o (p = 0.008), and d) State 3u (p = 0.04) respiration was decreased in endometrium from NHPs with endometriosis. One-way ANOVA, p < 0.05 considered significant. e) State 3 complex I-mediated OCR (p = 0.02) and f) complex I respiratory control rate (RCR, p = 0.01) was decreased in EMO compared to nEM. One-way ANOVA, p < 0.05 was considered significant. Sample sizes were nEM, n = 4; EM, n = 3; EMO, n = 3 for A-D and nEM, n = 5; EM, n = 4; EMO, n = 4 with multiple measurements per energy state for E and F

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