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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: Knockdown of vascular cell adhesion molecule 1 impedes transforming growth factor beta 1-mediated proliferation, migration, and invasion of endometriotic cyst stromal cells

Fig. 6

Silencing of VCAM-1 blocks the effects of TGF-β1 on the proliferation, migration, and invasion of endometriotic cyst stromal cells. Endometriotic cyst stromal cells were transfected with si-VCAM-1 or si-NC in the presence or absence of TGF-β1 (10 ng/mL) for different periods of time. a At 48 h post treatment, the protein expression of VCAM-1 was examined by western blotting. b and c The proliferation of endometriotic cyst stromal cells was determined by CCK-8 and EdU assays at the indicated time points. d and e At 48 h post treatment, the migration and invasion of endometriotic cyst stromal cells were determined by transwell migration and invasion assays. *P < 0.05, **P < 0.01, and ***P < 0.001

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