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Table 2 Patients and IVF cycle characteristics by pregnancy outcome

From: Effect of vitamin D status on normal fertilization rate following in vitro fertilization

Parameter

Pregnant

Not pregnant

P value

Live birth

No live birth

P value

Number of cycles

293

194

 

261

226

 

Age(y)

31.29 ± 3.53

32.63 ± 3.65

<0.001*

31.12 ± 3.41

32.64 ± 3.71

<0.001*

Duration of infertility(y)

3.54 ± 2.26

3.77 ± 2.43

0.284

3.45 ± 2.15

3.84 ± 2.52

0.065

BMI (kg/m2)

23.25 ± 3.34

23.74 ± 3.46

0.116

23.28 ± 3.34

23.62 ± 3.46

0.271

AMH (ng/ml)

5.31 ± 3.76

4.83 ± 3.55

0.160

5.41 ± 3.82

4.79 ± 3.50

0.065

bFSH (mIU/ml)

6.98 ± 1.74

7.10 ± 1.88

0.475

6.93 ± 1.74

7.14 ± 1.87

0.208

Season of blood drawing

 Spring (n, %)

41,54.7%

34,45.3%

0.209

37,14.2%

4,12.5%

0.706

 Summer (n, %)

83,

58.5%

59,41.5%

76,29.1%

7,21.9%

 Autumn (n, %)

83,68.0%

39,32.0%

74,28.4%

9,28.1%

 Winter (n, %)

86; 58.1%

62,41.9%

74,28.4%

12,37.5%

Previous pregnancy

 NO (n, %)

141, 48.1%

89, 45.9%

0.628

129,49.4%

106,46.9%

0.587

 Yes (n, %)

152, 51.9%

105, 54.1%

132,50.6%

120,53.1%

Infertility diagnosis

 Male factor (n, %)

11,3.8%

6,3.1%

0.426

10,3.8%

6,2.7%

0.688

 Tubal factor (n, %)

193,65.9%

125,64.4%

168,64.4%

150,66.4%

 Mixed (n, %)

41,14.0%

21,10.8%

38,14.6%

25,11.1%

 Endometriosis (n, %)

18,6.1%

11, 5.7%

16,6.1%

12,5.3%

 Anovulatory (n, %)

28,9.6%

27,13.9%

26,10.0%

29,12.8%

 Unexplained (n, %)

2,0.7%

4,2.1%

3,1.1%

4,1.8%

COH protocol

 Luteal phase agonist (n, %)

228,77.8%

138,71.1%

0.108

207,79.3%

159,70.4%

0.027*

 Antagonist (n, %)

65,22.2%

56,28.9%

54,20.7%

67,29.6%

Duration of stimulation (d)

9.08 ± 2.31

9.05 ± 2.06

0.908

9.06 ± 2.26

9.07 ± 2.16

0.962

Follicle≥16 mm on HCG day

7.74 ± 3.04

7.22 ± 2.96

0.059

7.78 ± 2.90

7.25 ± 3.13

0.055

Endometrial thickness on HCG day (mm)

11.75 ± 2.10

11.22 ± 2.24

0.008*

11.82 ± 2.09

11.21 ± 2.22

0.002*

Progestrone on HCG day (ng/ml)

0.92 ± 0.29

0.90 ± 0.33

0.578

0.92 ± 0.29

0.90 ± 0.33

0.332

Peak estradiol (pg/ml)

2602.72 ± 1142.74

2436.73 ± 1032.56

0.116

2625.10 ± 1114.09

2436.06 ± 1078.48

0.070

Oocytes retrieved (n)

8.39 ± 2.98

7.91 ± 3.28

0.094

8.50 ± 2.95

7.85 ± 3.25

0.020*

Mature oocytes (n)

7.03 ± 2.68

6.66 ± 2.99

0.156

7.15 ± 2.68

6.58 ± 2.92

0.024*

Normal fertilization rate (%)

72.55 ± 17.70

73.19 ± 20.05

0.710

72.22 ± 17.18

73.48 ± 20.23

0.456

High quality embryo rate (%)

59.5%

57.1%

0.199

58.4%

51.6%

0.001*

Blastocyst formation rate (%)

66.33 ± 31.39

62.75 ± 34.51

0.273

66.06 ± 31.59

63.61 ± 33.90

0.443

Embryos transferred (n)

1.96 ± 0.21

1.92 ± 0.28

0.082

1.96 ± 0.20

1.92 ± 0.27

0.081

  1. *Values are significantly different between groups (P < 0.05)