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Table 2 Patients and IVF cycle characteristics by pregnancy outcome

From: Effect of vitamin D status on normal fertilization rate following in vitro fertilization

Parameter Pregnant Not pregnant P value Live birth No live birth P value
Number of cycles 293 194   261 226  
Age(y) 31.29 ± 3.53 32.63 ± 3.65 <0.001* 31.12 ± 3.41 32.64 ± 3.71 <0.001*
Duration of infertility(y) 3.54 ± 2.26 3.77 ± 2.43 0.284 3.45 ± 2.15 3.84 ± 2.52 0.065
BMI (kg/m2) 23.25 ± 3.34 23.74 ± 3.46 0.116 23.28 ± 3.34 23.62 ± 3.46 0.271
AMH (ng/ml) 5.31 ± 3.76 4.83 ± 3.55 0.160 5.41 ± 3.82 4.79 ± 3.50 0.065
bFSH (mIU/ml) 6.98 ± 1.74 7.10 ± 1.88 0.475 6.93 ± 1.74 7.14 ± 1.87 0.208
Season of blood drawing
 Spring (n, %) 41,54.7% 34,45.3% 0.209 37,14.2% 4,12.5% 0.706
 Summer (n, %) 83,
58.5%
59,41.5% 76,29.1% 7,21.9%
 Autumn (n, %) 83,68.0% 39,32.0% 74,28.4% 9,28.1%
 Winter (n, %) 86; 58.1% 62,41.9% 74,28.4% 12,37.5%
Previous pregnancy
 NO (n, %) 141, 48.1% 89, 45.9% 0.628 129,49.4% 106,46.9% 0.587
 Yes (n, %) 152, 51.9% 105, 54.1% 132,50.6% 120,53.1%
Infertility diagnosis
 Male factor (n, %) 11,3.8% 6,3.1% 0.426 10,3.8% 6,2.7% 0.688
 Tubal factor (n, %) 193,65.9% 125,64.4% 168,64.4% 150,66.4%
 Mixed (n, %) 41,14.0% 21,10.8% 38,14.6% 25,11.1%
 Endometriosis (n, %) 18,6.1% 11, 5.7% 16,6.1% 12,5.3%
 Anovulatory (n, %) 28,9.6% 27,13.9% 26,10.0% 29,12.8%
 Unexplained (n, %) 2,0.7% 4,2.1% 3,1.1% 4,1.8%
COH protocol
 Luteal phase agonist (n, %) 228,77.8% 138,71.1% 0.108 207,79.3% 159,70.4% 0.027*
 Antagonist (n, %) 65,22.2% 56,28.9% 54,20.7% 67,29.6%
Duration of stimulation (d) 9.08 ± 2.31 9.05 ± 2.06 0.908 9.06 ± 2.26 9.07 ± 2.16 0.962
Follicle≥16 mm on HCG day 7.74 ± 3.04 7.22 ± 2.96 0.059 7.78 ± 2.90 7.25 ± 3.13 0.055
Endometrial thickness on HCG day (mm) 11.75 ± 2.10 11.22 ± 2.24 0.008* 11.82 ± 2.09 11.21 ± 2.22 0.002*
Progestrone on HCG day (ng/ml) 0.92 ± 0.29 0.90 ± 0.33 0.578 0.92 ± 0.29 0.90 ± 0.33 0.332
Peak estradiol (pg/ml) 2602.72 ± 1142.74 2436.73 ± 1032.56 0.116 2625.10 ± 1114.09 2436.06 ± 1078.48 0.070
Oocytes retrieved (n) 8.39 ± 2.98 7.91 ± 3.28 0.094 8.50 ± 2.95 7.85 ± 3.25 0.020*
Mature oocytes (n) 7.03 ± 2.68 6.66 ± 2.99 0.156 7.15 ± 2.68 6.58 ± 2.92 0.024*
Normal fertilization rate (%) 72.55 ± 17.70 73.19 ± 20.05 0.710 72.22 ± 17.18 73.48 ± 20.23 0.456
High quality embryo rate (%) 59.5% 57.1% 0.199 58.4% 51.6% 0.001*
Blastocyst formation rate (%) 66.33 ± 31.39 62.75 ± 34.51 0.273 66.06 ± 31.59 63.61 ± 33.90 0.443
Embryos transferred (n) 1.96 ± 0.21 1.92 ± 0.28 0.082 1.96 ± 0.20 1.92 ± 0.27 0.081
  1. *Values are significantly different between groups (P < 0.05)