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Table 1 Characteristics of the Patients at Baseline According Age and AMH Level

From: IVF outcomes of women with discrepancies between age and serum anti-Müllerian hormone levels

Characteristic

Age<35 yrs

Age ≥ 35 yrs

young

low-AMH

(N = 1819)

young

average-AMH

(N = 3642)

young

high-AMH

(N = 1822)

older

low-AMH

(N = 537)

older

average-AMH

(N = 1074)

older

high-AMH

(N = 537)

AMH range[%(ng/ml)]

0-25th

quartile (0.01–1.32)

25th–75th

quartile (1.32–3.99)

75th–100th

quartile (3.99–22.05)

0-25th

quartile (< 0.01–0.62)

25th–75th

quartile (0.63–2.41)

75th–100th quartile (2.41–22.05)

Age (yrs)

29.46 ± 3.18

28.74 ± 3.16

28.26 ± 3.10

38.67 ± 2.90

37.88 ± 2.57

37.12 ± 2.16

BMI (kg/m2)

23.12 ± 3.69

22.90 ± 3.42

22.82 ± 3.62

24.00 ± 3.15

24.11 ± 3.19

23.99 ± 3.29

AFC

10.52 ± 4.78a,b

14.46 ± 5.80c

19.78 ± 9.41

7.14 ± 2.93d,e

10.47 ± 5.38f

15.18 ± 7.04

Fertility history

 Previous conception[%(n/N)]

41.67(758/1819)g

39.07(1423/3642)

34.69(632/1822)

72.75(388/537)

74.77(803/1074)

66.85(359/537)

Concomitant infertility factors

 Tubal factors[%(n/N)]

66.08(1202/1819)b

64.74(2358/3642)c

60.21(1097/1822)

68.34(367/537)

71.79(771/1074)

70.58(379/537)

Ovulatory dysfunction[%(n/N)]

 PCOS[%(n/N)]

2.25(41/1819)a,b

7.36(268/3642)c

23.49(428/1822)

0.56(3/537)e

1.96(21/1074)f

10.80(58/537)

 POI[%(n/N)]

5.22(95/1819)a,b

0.41(15/3642)

0(0/0)

8.39(45/537)d,e

1.96(21/1074)

0.19(1/537)

 Male factors[%(n/N)]

30.90(562/1819)a,b

36.55(1331/3642)

37.87(690/1822)

22.91(123/537)

26.44(284/1074)

25.14(135/537)

Controlled Ovarian Hyperstimulation outcome

 Gonadotropin start dose (IU)

196.40 ± 48.96a,b

177.05 ± 44.02c

162.95 ± 42.41

230.48 ± 49.82d,e

218.14 ± 48.73f

197.69 ± 41.29

 Total Gonadotropin dose (IU)

2130.27 ± 982.84g

1937.00 ± 778.37

1782.24 ± 762.80

2375.30 ± 1108.22

2286.36 ± 970.59

2140.51 ± 800.74

 No. of days of ovarian stimulation

10.52 ± 2.02g

10.82 ± 1.78

10.94 ± 1.95

10.06 ± 2.28

10.41 ± 2.03

10.85 ± 1.93

 Endometrial thickness on hCG trigger day(cm)

1.11 ± 0.20

1.13 ± 0.18

1.12 ± 0.18

1.02 ± 0.23d,e

1.07 ± 0.20

1.10 ± 0.20

  1. AMH anti-Müllerian hormone, BMI body Mass Index, AFC antral follicle count
  2. Continuous data was presented as mean ± standard deviation, and categorical variable was presented as percentile (number)
  3. Significant subgroup differences (Bonferroni pairwise comparison, p < 0.05/3) are indicated by superscripts “a: low AMH vs. average AMH in women < 35 yrs”, “b: low AMH vs. high AMH in women < 35 yrs”, “c: average AMH vs. high AMH in women < 35 yrs”, “d: low AMH vs. average AMH in women ≥35 yrs”, “e significant difference for low AMH vs. high AMH in women ≥35 yrs”,“f significant difference for average AMH vs. high AMH in women ≥35 yrs” g: p < 0.05 was considered statistically significant difference for main effect