Table 1 iTRAQ analysis of differentially expressed proteins between the RPL and the control group
From: Quantitative proteomic analysis of sperm in unexplained recurrent pregnancy loss
Uniprot ID | Protein Name | Gene Name | Log2FC | P value |
|---|---|---|---|---|
Up-regulated proteins | ||||
 P04279 | Semenogelin-1 | SEMG1 | 2.27 | 1.51E-08 |
 P02751 | Fibronectin | FN1 | 1.24 | 7.50268E-05 |
 A0A0U1RQF0 | Fatty acid synthase | FASN | 1.21 | 2.09185E-06 |
 E7EQB2 | Lactotransferrin | LTF | 2.14 | 3.04345E-11 |
 P35579 | Myosin-9 | MYH9 | 1.36 | 1.05659E-05 |
 Q02383 | Semenogelin-2 | SEMG2 | 1.62 | 0.027249441 |
 O75369 | Filamin-B | FLNB | 0.73 | 0.033877425 |
 P50991 | T-complex protein 1 | CCT4 | 1.06 | 0.017997051 |
 P53396 | ATP-citrate synthase | ACLY | 0.84 | 0.038844213 |
 P35580 | Myosin-10 | MYH10 | 1.12 | 0.002368773 |
 P12277 | Creatine kinase B | CKB | 1.29 | 0.002233567 |
 P62258 | 14–3-3 protein epsilon | YWHAE | 1.09 | 0.033955991 |
 P27487 | Dipeptidyl peptidase 4 | DPP4 | 0.85 | 0.016909158 |
 Q00796 | Sorbitol dehydrogenase | SORD | 1.77 | 0.01105386 |
 P12273 | Prolactin-inducible protein | PIP | 1.75 | 0.014142492 |
 Q6UX06 | Olfactomedin-4 | OLFM4 | 2.03 | 0.041974943 |
 P49221 | Glutamyltransferase 4 | TGM4 | 1.85 | 0.048483204 |
 P08670 | Vimentin | VIM | 0.98 | 0.023722751 |
 O43175 | Phosphoglycerate dehydrogenase | PHGDH | 2.01 | 0.01025431 |
 P31947 | 14–3-3 protein sigma | SFN | 1.01 | 0.011000973 |
 P09525 | Annexin A4 | ANXA4 | 1.25 | 0.021621821 |
 O43776 | Asparagine--tRNA ligase | NARS | 1.29 | 0.031847354 |
 P47895 | Aldehyde dehydrogenase | ALDH1A3 | 1.42 | 0.045620359 |
 X6RBG4 | Uromodulin | UMOD | 2.74 | 0.043337822 |
 C9JC07 | Myeloid-associated differentiation marker | MYADM | 5.50 | 0.013526945 |
Down-regulated proteins | ||||
 Q5JQC9 | A-kinase anchor protein 4 | AKAP4 | −1.50 | 1.12E-09 |
 O75969 | A-kinase anchor protein 3 | AKAP3 | −1.25 | 1.17548E-05 |
 P19367 | Hexokinase-1 | HK1 | −0.60 | 0.002458935 |
 Q8NEB7 | Acrosin-binding protein | ACRBP | −0.82 | 0.03690489 |
 J3QTJ6 | Fibrous sheath-interacting protein 2 | FSIP2 | −1.18 | 2.85668E-06 |
 O75976 | Carboxypeptidase D | CPD | −0.78 | 0.004574668 |
 Q8TEX9 | Importin-4 | IPO4 | −1.20 | 0.002037515 |
 Q8TC56 | Protein FAM71B | FAM71B | −0.92 | 0.00900713 |
 Q9BXF9 | Tektin-3 | TEKT3 | −0.70 | 0.016060278 |
 A0A0C4DGB6 | Serum albumin | ALB | −1.28 | 0.006274223 |
 A0A0G2JML4 | C6orf10 | C6orf10 | −1.01 | 0.041954588 |
 Q6ZU69 | Protein FAM205A | FAM205A | −1.26 | 0.010902458 |
 Q9UII2 | ATPase inhibitor, mitochondrial | ATPIF1 | −1.01 | 0.035165988 |