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Table 1 the cf-nDNA and the relative cf-mtDNA (cf-ND1/cf-β-globin ratio) levels in human follicular fluids for oocytes performing IVF or ICSI

From: Cell-free mitochondrial DNA in human follicular fluid: a promising bio-marker of blastocyst developmental potential in women undergoing assisted reproductive technology

  Total IVF ICSI
FF associated with n of FF(%) cf-nDNA MD (IQR) relative cf-mtDNA MD (IQR) n of FF(%) cf-nDNA MD (IQR) relative cf-mtDNA MD (IQR) n of FF(%) cf-nDNA MD (IQR) relative cf-mtDNA MD (IQR)
Mature oocytes (MII) 190 (91.79) 0.24 (0.13–0.48) 5.70 (3.66–9.97) 118 (91.47) 0.21 (0.11–0.53) 5.80 (3.90–9.40) 72 (92.31) 0.25 (0.14–0.36) 5.56 (3.23–10.05)
Immature oocytes (MI or GV) 17 (8.21) 0.13 (0.07–0.30) 6.50 (4.82–11.18) 11 (8.53) 0.19 (0.06–0.29) 6.51 (3.88–14.86) 6 (7.69) 0.12 (0.09–0.13) 6.63 (5.03–7.83)
Fertilized oocytes 170 (81.34) 0.23 (0.13–0.46) 6.06 (3.90–10.01) 106 (80.92) 0.21 (0.11–0.50) 6.51 (4.02–10.01) 64 (82.05) 0.25 (0.14–0.38) 5.46 (2.99–10.01)
Unfertilized oocytes 39 (18.66) 0.18 (0.08–0.37) 5.57 (3.72–10.16) 25 (19.08) 0.20 (0.07–0.50) 5.11 (2.88–10.23) 14 (17.95) 0.13 (0.09–0.26) 7.78 (4.94–9.97)
  1. Data are presented as MD (IQR). Percentages are calculated within groups. FF follicular fluid. MI metaphase I, MII metaphase II, GV germinal vesicle, MD Median, IQR interquartile range