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Table 4 Comparison of Mean ± SEM TH-ir neuronal cells of control, estradiol, BPA 2 μg/kg, BPA 200 μg/kg, BPS 2 μg/kg, BPS 200 μg/kg treated groups, in 20 μm thick hypothalamic sections of 28 days old male rats

From: Comparative study of environmental pollutants bisphenol A and bisphenol S on sexual differentiation of anteroventral periventricular nucleus and spermatogenesis

Animals

Control

Estradiol 50 μg/kg

BPA 2 μg/kg

BPA 200 μg/kg

BPS 2 μg/kg

BPS 200 μg/kg

1

74.5

60.75

75

163.75

183

148

2

46.25

56.25

101

178.25

100.75

119.5

3

65.25

56.5

94.75

56.5

64.5

87

TH-ir Cell Bodies

62 ± 4.47

57.83 ± 3.68

90.25 ± 7.41b*

175 ± 8.2abc***

80.08 ± 10.03d***

118.16 ± 10.23abd***e*

  1. Values are expressed as mean SEM
  2. *p < 0.05, **p < 0.01, p*** < 0.001
  3. a = Values vs control, b = Values vs Bisphenol A 2 μg/kg, c = Values vs Bisphenol A 200 μg/kg, d = Values vs Bisphenol S 2 μg/kg