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Table 2 Analyzed embryo characteristics and clinical outcomes

From: Blastomere movement post first cell division correlates with embryonic compaction and subsequent blastocyst formation

  

Blastomere movement type

 

Total

Bouncing

Wobbling

Twist-and-crumble

No. of cleaved embryos analyzed

966

543 (56.2)

194 (20.1)

229 (23.7)

 Four-cell stage embryos

964 (99.8)

543 (100)

194 (100)

228 (99.6)

 Eight-cell stage embryos

900 (93.2)

516 (95.0)a

181 (93.3)a

202 (88.2)b

 Morula

842 (87.2)

493 (90.8)a

167 (86.1)a,b

180 (78.6)b

 Blastocysts

731 (75.7)

435 (80.1)a

144 (74.2)a,b

152 (66.4)b

 Blastocysts expanded

681 (70.5)

406 (74.8)a

136 (70.1)a,b

139 (60.7)b

 Blastocysts cryopreserved

625 (64.7)

378 (69.6)a

124 (63.9)a

123 (53.7)b

 Morphological grade of blastocysts

  ICM

    

   Grade A

291 (46.6)

184 (48.7)

59 (47.6)

48 (39.0)

   Grade B

214 (34.2)

129 (34.1)

37 (29.8)

48 (39.0)

   Grade C

120 (19.2)

65 (17.2)

28 (22.6)

27 (22.0)

  TE

   Grade A

267 (42.7)

177 (46.8)a

56 (45.2)a

34 (27.6)b

   Grade B

178 (28.5)

97 (25.7)a

35 (28.2)a,b

46 (37.4)b

   Grade C

180 (28.8)

104 (27.5)

33 (26.6)

43 (35.0)

No. of blastocysts thawed

499

298

102

99

No. of survived blastocysts

496 (99.3)

297 (99.7)

101 (99.0)

98 (99.0)

No. of blastocysts transferred

496

297

101

98

Morphological grade of blastocysts transferred

  ICM

   Grade A

250 (50.3)

157 (52.7)

52 (51.5)

41 (41.8)

   Grade B

158 (31.9)

90 (30.4)

33 (32.7)

35 (35.7)

   Grade C

88 (17.8)

50 (16.9)

16 (15.8)

22 (22.5)

  TE

   Grade A

235 (47.3)

155 (52.0)a

50 (49.5)a

30 (30.6)b

   Grade B

128 (25.9)

65 (22.0)a

27 (26.7)a,b

36 (36.7)b

   Grade C

133 (26.9)

77 (26.0)

24 (23.8)

32 (32.7)

Clinical pregnancies

234 (47.2)

136 (45.8)

47 (46.5)

51 (52.0)

Ongoing pregnancies

201 (40.5)

115 (38.7)

41 (40.6)

45 (45.9)

Follow-up data on live birth (ET date: April–December 2017)

246

149

53

44

 Live birth

88 (35.8)

52 (34.9)

18 (34.0)

18 (40.9)

dBMov

3.84 ± 0.07 [0.16–25.54]

2.82 ± 0.05a [0.16–8.49]

5.20 ± 0.13b [0.734–14.57]

5.36 ± 0.17b [0.63–25.54]

dBMov/(t3-t2)

0.366 ± 0.007 [0.014–1.000]

0.253 ± 0.004a [0.014–0.727]

0.497 ± 0.015b [0.071–1.000]

0.523 ± 0.016b [0.061–1.000]

  1. Categorical data are presented as n (%), continuous data are presented as mean ± standard error of the mean [range]. Different superscript letters (a, b) indicate a significant difference at P <  0.05. Abbreviations: dBMov, blastomere movement duration; dBMov/(t3-t2), ratio of the duration of blastomere movement at the 2-cell stage; ICM, inner cell mas; ET, embryo transfer; TE, trophectoderm