Fig. 1

Adipocyte size in peri-gonadal adipose tissue increases with advanced reproductive age. a Representative anatomical images showing the ovary (yellow arrow) and the surrounding peri-gonadal adipose tissue (white arrow) in reproductively young and old mice. b Representative images of histological sections of peri-gonadal adipose tissue from reproductively young and old mice stained with PSR. The scale bars = 200 μm. c The average cross-sectional adipocyte area (μm2) in peri-gonadal adipose tissue from reproductively young (green) and old (red) mice. b The average number of adipocytes per 10,000 μm2 in peri-gonadal adipose tissue from reproductively young (green) and old (red) mice. Error bars represent standard error between samples. *P value ≤0.05 by t-test.