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Table 3 Signal molecules that showed significant changes during this period

From: Intercellular wireless communication network between mother and fetus in rat pregnancy-a study on directed and weighted network

Gestation period Cytokines P-value Rate of change in concentration Statistical analysis method
E1 LH 0.021* 0.694 Comparative t-test
BDNF 0.013* −0.425 Comparative t-test
E5 MCP-1 0.012* 23.5 Nonparametric test
IL-10 0.016* 0.918 Comparative t-test
IL-13 0.012* 119.0 Comparative t-test
GRO 0.063 8.47 Comparative t-test
E7 Leptin 0.029* 1.46 Comparative t-test
IL-1α 0.037* 14.4 Comparative t-test
IP-10 0.041* 5.11 Comparative t-test
IFN-γ 0.059 26.4 Comparative t-test
E9 GH 0.045* 4.05 Comparative t-test
E13 Leptin 0.093 1.12 Comparative t-test
E15 LH 0.047* −0.590 Comparative t-test
E17 RANTES 0.002** −0.279 Comparative t-test
GH 0.039* 4.19 Comparative t-test
LH 0.080 −0.519 Comparative t-test
E19 Leptin 0.005** 1.91 Comparative t-test
TSH 0.001** 1.79 Comparative t-test
ACTH 0.049* −0.477 Comparative t-test
GH 0.065 3.72 Comparative t-test
E21 ACTH 0.002** −0.757 Comparative t-test
BDNF 0.005** −0.484 Comparative t-test
IL-2 0.017* 2.77 Comparative t-test
IL-6 0.013* 0.755 Comparative t-test
IL-12P70 0.017* 1.11 Comparative t-test
IL-18 0.018* 3.33 Comparative t-test
IFN-γ 0.044* 29.9 Comparative t-test
Leptin 0.054 1.28 Comparative t-test
GRO 0.060 8.55 Comparative t-test
E23 ACTH 0.036* −0.507 Comparative t-test
BDNF 0.008** −0.458 Comparative t-test
D1 VEGF 0.008** 1.61 Nonparametric test
BDNF 0.002** −0.531 Comparative t-test
ACTH 0.022* −0.559 Comparative t-test
D3 PRL < 0.001** 4.70 Comparative t-test
ACTH 0.023* −0.552 Comparative t-test
LH 0.030* −0.648 Comparative t-test
  1. *P < 0.05, **P < 0.01
  2. E (during the period of pregnancy), D (post partum)