Fig. 7

Characteristic signaling molecules with significant changes at pregnancy days 5, 7, 17, 19, and 21. Three characteristic signaling molecules, including MCP-1, IL-10 and IL-13, are increased significantly at pregnancy day 5. At day 7, IL-1α and IP-10 are markedly increased. At day 17, RANTES is the characteristic signaling molecule showing decreased levels. At day 19, TSH is the characteristic molecule with increased amounts. At day 21, 4 characteristic signaling molecules, including IL-2, IL-6, IL-12p70 and IL-18, are increased significantly