Fig. 2

Altered expression of genes affecting appetite and insulin sensitivity. a Leptin mRNA levels were reduced by Let-7b mimic and increased by Let-7b inhibitor and miR 342-3p mimic. b Adipoq mRNA levels were reduced by Let-7b mimic. c IL-6 mRNA levels were reduced by Let-7b and 342-3p mimics, and increased by Let-7b and 342-3p inhibitors. d HSL mRNA levels were reduced by Let-7b mimic and increased by Let-7b inhibitor, and decreased by both 342-3p mimic and inhibitor. Each bar represents the mean ± SE for data from three individual experiments and each experiment was performed in triplicate. * denotes statistical significance (p < 0.05) compared to the negative controls while ** denotes p < 0.01