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Table 4 Linear mixed models noting association between the main outcomes using PCOS status as covariate adjusted by follicular stage

From: Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state

Primary Outcomes

β (95% CI)

P-Value

p-value (interaction)*

Mean Total Area

Risk Factors

PCOS

514 (− 2821 to 3849)

0.76

NS

Follicular type

 small

Ref

  

 medium

1384 (−500 to 3269)

0.15

 

 large

10,765 (8774 to 12,757)

> 0.001

 

 large & preovulatory

6974 (4008 to 9941)

> 0.001

 

Percentage of Staining

Risk Factors

PCOS

0.28 (−14.1 to 14.0)

0.96

NS

Follicular type

   

 small

Ref

  

 medium

5.98 (2.75 to 9.22)

< 0.001

 

 large

−0.37 (−3.82 to 3.07)

0.83

 

 large & preovulatory

4.5 (−0.70 to 9.78)

0.09

 

Average Intensity of Staining

Risk Factors

PCOS

−5.4 (−12.74 to 1.9)

0.15

NS

Follicular type

   

 small

Ref

  

 medium

18.02 (8.9 to 27)

> 0.001

 

 large

12.05 (2.7 to 21.4)

0.25

 

 large & preovulatory

−4.4 (−30.9 to 22.0)

0.74

 
  1. *Test of possible interaction between PCOS status and follicular size on the three outcomes. NS = not significant