Skip to main content

Table 1 Expression and distribution of the plasminogen system markers in control and PCOS mice ovaries

From: Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state

 

Granulosa cells

Theca cells

Large follicles

Small follicles

General distribution

 

Con

PCOS

Con

PCOS

Con

PCOS

Con

PCOS

Con

PCOS

PAI-1

+

+

+

+

P

T

tPA

A

A

uPA

+

+

+

+

+

+

P

P

Plasminogen/Plasmin

+

+

+

+

P

P

Plasminogen only

+

+

+/−

+

+

+

+

T

T

  1. ‘+’ = expression of marker; ‘-’ = marker absent or in low levels. PAI-1, plasminogen activator inhibitor-1; tPA, tissue plasminogen activator; uPA, urokinase plasminogen activator; Con, controls; P, peripheral; C, central; T, throughout; A, absent. The small follicles described typically represent primordial and primary follicles while the large follicles include secondary and Graafian follicles