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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state

Fig. 3

Expression of plasminogen activators uPA and tPA in normal and PCOS mouse ovaries. Left: Top: (a) uPA and Bottom: (b) tPA. Representative histological images are from normal (control) (Ai, Aiii, Bi, Biii) or PCOS ovaries (Aii, Aiv, Bii, Biv) stained with an (a) anti-uPA or (b) anti-tPA antibody. The scale bar represents 500 μm for Ai, Aii, Bi & Bii, 200 μm for Aiii & Biv and 100 μm for Aiv & Biii. Right: Top: Negative control for uPA on mouse kidney and graphical representation comparing the percentage of ovarian staining (Area Fraction ROI) for uPA between normal and PCOS ovaries for 6 replicates of each experimental group (mean ± SD) and Bottom: Negative control for tPA on mouse brain and graphical representation comparing the percentage of ovarian staining (Area Fraction ROI) for tPA between normal and PCOS ovaries for 6 replicates of each experimental group (mean ± SD)

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