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Table 3 Adjusted odds ratios of MZT by method of fertilization and stage of embryo transfer in ART cycles

From: The risk of secondary sex ratio imbalance and increased monozygotic twinning after blastocyst transfer: data from the Japan Environment and Children’s Study

 

AOR

95% CI

P-value

Spontaneous conception

1.000 (reference)

  

Non-ART treatment

0.426

(0.158–1.149)

NS

CT

1.167

(0.287–4.740)

NS

BT

4.229

(2.614–6.844)

< 0.001

  1. Adjusted for the questionnaire results for mother’s age, BMI, metabolic equivalent/min, calorie intake, education, income, smoking status, alcohol intake status, SF-8 physical component summary, SF-8 mental component summary, K6 and history of hyperlipidemia, diabetes, hyperthyroidism, hypothyroidism and the questionnaire results for father’s age, BMI, low education, smoking status, alcohol intake status, SF-8 physical component summary, SF-8 mental component summary, K6
  2. CT (early cleavage-stage embryo transfer), BT (blastocyst transfer), AOR (adjusted odds ratio), CI (confidence interval), NS (not statistically significant)