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Table 3 Comparison of FSH, LH, Testosterone, and prolactin before and after treatment with NAC. Significant reduction of serum LH, FSH and, significant increase of serum testosterone levels was observed after treatment with NAC compared to before treatment

From: Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men

Hormonal analysis

Before NAC (n = 50)

After NAC (n = 50)

P-Value

FSH (mIU/mL)

4.14 ± 0.17

3.67 ± 0.19

0.01

LH (mIU/mL)

4.20 ± .060

4.07 ± .054

0.04

Testosterone (ng/mL)

3.87 ± 0.15

4.37 ± 0.17

0.01

PRL (ng/ml)

10.61 ± 0.37

10.60 ± 0.37

0.193

  1. FSH: Follicle stimulating hormone, LH: Luteinizing hormone, PRL: Prolactin, NAC: N-acetylcysteine. Significant differences in bold