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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

Fig. 3

Number of follicles per ovary (H&E-stain). Number of follicles of various stages of development per ovary is shown. The number of follicles showed no significant difference in primary follicles (DMF group: 108.2 ± 38.7 vs control group: 75.2 ± 14.3, p = 0.12), secondary follicles (DMF group: 23.5 ± 10.0 vs control group: 21.6 ± 5.9, p = 0.72), and antral follicles (DMF group: 7.5 ± 3.7 vs control group: 8.0 ± 1.5, p = 0.81), but approximately 60% more primordial follicles (DMF group: 395.0 ± 15.8 vs control group: 251.2 ± 17.3, p = 0.0002) were preserved in DMF group. The number of samples was n = 6 each

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