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Table 4 Profile of Y chromosome-linked specific gene-associated DNA inserts in endometrial samples

From: Genomic evidence of Y chromosome microchimerism in the endometrium during endometriosis and in cases of infertility

Target

Total number of samples with positive insert/Total number of samples (Range of copy numbers)1

Control (CON)

Endometriosis OE)

Fertile (FCON)

Infertile (ICON)

Fertile (FOE)

Infertile (IOE)

BAGE

6/6

5/9

0/9**

9/9

(3.5–3.7)

(2.4–3.2)

 

(2.0–3.1)

EIF1AY

6/6

5/9

4/9

6/9

(2.1–3.5)

(2.4–3.3)

(3.0–3.4)

(1.1–3.1)

KDM5D2

0/6

0/9

0/9

0/9

NLGN4Y

6/6

6/9

6/9

6/9

(2.4–3.3)

(2.4–3.9)

(3.3–3.6)

(1.2–3.0)

PRKY

6/6

3/9

0/9**

2/9

(2.1–2.5)

(1.4–2.1)

 

(0.1–1.6)

SRY

0/6

0/9

0/9

0/9

TTTY9A

6/6

3/9

0/9**

2/9

(0.8–0.9)

(0.8–1.0)

 

(−0.6–0.4)**

TTTY14

6/6

9/9

9/9

9/9

(3.6–3.7)

(3.6–3.7)

(3.5–3.7)

(3.5–3.7)

ZFY

6/6

9/9

3/9

9/9

(3.2–3.5)

(2.9–3.5)

(1.0–2.7)*

(3.2–3.4)

  1. 1In logarithmic scale. No detectable amplifications and very high Cq values (> 35) were considered as not detectable and shown as 0-value. 2Variants 1–3. *P < 0.05, **P < 0.02 compared with group 1A. BAGE, B melanoma antigen; KDM5D, lysine demethylase 5D; PRKY, protein kinase Y-linked; SRY, sex determining region Y; TTTY9A, testis-specific transcript Y-linked 9A; TTTY14, testis-specific transcript Y-linked 14; ZFY, zinc finger protein Y-linked. The prevalence data were tested using Fisher’s exact test and the copy number data were tested using Kruskal-Wallis followed by the Mann-Whitney U-test