Antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) are the predictors of natural fecundability have similar trends irrespective of fertility status and menstrual characteristics among fertile and infertile women below the age of 40 years

Table 4 Mean proportion of antral follicles among different age-specific groups of infertile patients and controls

Age Groups	Infertile patient Age groups			Control Age groups			Mean difference (95% Cl)	Infertile versus control p-value
Age Groups	25–28	29–35	36–39	25–28	29–35	36–39	Mean difference (95% Cl)	Infertile versus control p-value
No of samples n (%)	90 (21.2)	210 (49.6)	123 (29.07)	101 (26.03)	165 (42.5)	122 (31.4)
Total AFC [median (95% population limits)]	27.1 (23.9;30.1)	23.0 (22.3;25.2)	17.1 (15.3;19.9)	28.9 (24.8;31.2)	23.4 (19.7;25.6)	16.9 (14.9;19.8)	−0.29 (−2.01;1.33)	0.6
AFC (mm), mean proportion (95% population limits)
AFC 2–5	0.71 (0.7;0.72)	0.68 (0.61;0.76)	0.61 (0.59;0.72)	0.8 (0.71;0.79)	0.76 (0.61;0.72)	0.68 (0.64;0.69)	−0.06 (− 0.09; −0.03)	< 0.001
AFC 5–8	0.41 (0.37;0.36)	0.42 (0.38;0.44)	0.44 (0.39;0.41)	0.31 (0.28;0.32)	0.3 (0.29;0.32)	0.3 (0.26;0.32)	0.03 (−0.005;0.054)	0.2
AFC 8–10	0.06 (0.03;0.08)	0.07 (0.05;0.08)	0.08 (0.07;0.98)	0.04 (0.03;0.04)	0.04 (0.03;0.05)	0.05 (0.05;0.07)	0.04 (0.03;0.05)	< 0.001

Data are presented as [median (95% population limits)] and number [%age]. Premutation tests were used to estimate the mean differences. P-values were calculated through bootstrapping and p > 0.05 considered statistically significant

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