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Table 2 Menstrual characteristics in women under the age of 40 years

From: Antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) are the predictors of natural fecundability have similar trends irrespective of fertility status and menstrual characteristics among fertile and infertile women below the age of 40 years

Parameters

Infertile Patient Age groups (years)

Control Age groups (years)

Infertile vs. controls p-value

25–28

29–35

36–39

p- value

Total

25–28

29–35

36–39

p- value

Total

Number of women [n (%)]

90 (21.2)

210 (49.6)

123 (29.07)

423 (100)

101 (26.01)

165 (42.5)

122 (31.4)

388 (100)

Age at menarche (years) n (%)]

  ≤ 11

12 (3.3)

35 (16.6)

24 (19.5)

0.1c

71 (16.7)

8 (7.9)

11 (6.6)

14 (11.4)

0.2c

33 (8.5)

0.09c

 12–13

49 (54.4)

108 (51.4)

59 (47.9)

 

216 (51)

79 (78.2)

98 (59.3)

23 (18.8)

 

200 (51.5)

 

 13–14

10 (11.1)

45 (25.7)

31 (14.7)

 

86 (20.3)

12 (11.8)

41 (24.8)

81 (66.3)

 

134 (34.5)

 

  ≥ 15

19 (21.1)

22 (10.4)

9 (7.3)

 

50 (11.8)

2 (1.9)

15 (9)

4 (3.2)

 

21 (5.4)

 

 Menstrual Cycle length (days) [mean ± SD]

33.4 ± 3.1

29.9 ± 1.9

28.8 ± 1.8

0.4a

30.2 ± 2.0

28.9 ± 2.1

29.1 ± 2.3

30.2 ± 1.9

0.3a

29.9 ± 2.1

0.5a

Frequency of Menses (days) [n (%)]

 Frequent (< 21)

31 (34.4)

85 (40.4)

35 (28.4)

< 0.001c

151 (35.6)

1 (0.99)

0 (0.00)

1 (0.08)

< 0.001c

2 (0.51)

0.01c

 Normal (24–38)

14 (15.5)

46 (21.9

29 (23.5)

 

89 (21)

100 (99.0)

164 (99.3)

121 (99.1)

 

385 (99.2)

 

 Infrequent (> 38)

45 (50)

79 (37.6)

59 (47.9)

 

183 (43.2)

0 (0)

1 (0.6)

0 (0)

 

1 (0.25)

 

Cycle to Cycle variation over 12 months (days) [n (%)]

 Regular (variation ±2–20 days)

15 (16.6)

29 (13.8)

14 (11.3)

< 0.002c

58 (13.7)

101 (100)

165 (100)

121 (99.1)

< 0.001c

387 (99.8)

0.03c

 Irregular (variations > 20 days)

75 (83.3)

190 (90.4)

109 (88.6)

 

374 (88.4)

0 (0)

0 (0)

1 (0)

 

1 (0.25)

 

Duration of blood flow (days) [n (%)]in one episode

 Prolonged (> 8)

23 (25.5)

65 (30.9)

31 (25.2)

< 0.001c

119 (28.1)

19 (18.8)

35 (21.2)

15 (12.2)

< 0.001c

69 (17.7)

0.2c

 Normal (4–8)

12 (3.3)

35 (16.6)

19 (15.4)

 

66 (15.6)

53 (79.2)

80 (48.4)

62 (50.8)

 

195 (50.2)

 

 Shortened (<  4)

55 (61.1)

110 (52.3)

73 (59.3)

 

238 (56.2)

29 (28.7)

50 (30.3)

45 (36.8)

 

123 (31.7)

 

Monthly blood loss (ml) [n (%)]

 Light (< 5)

23 (25.5)

73 (34.7)

15 (12.1)

< 0.001c

111 (26.2)

18 (17.8)

22 (13.3)

60 (49.1)

< 0.001c

100 (25.7)

0.3c

 Normal (5–80)

25 (27.7)

49 (23.3)

10 (8.1)

 

84 (19.8)

55 (54.4)

101 (61.2)

52 (42.6)

 

208 (53.6)

 

 Heavy (> 80)

20 (22.2)

63 (30)

36 (29.2)

 

119 (28.1)

25 (24.7)

40 (24.2)

10 (8.1)

 

137 (35.3)

 

 No bleeding

22 (24.4)

25 (11.9)

38 (30.8)

 

85 (20)

0 (0)

0 (0)

0 (0)

 

0 (0)

 

Occurrence of Blood clots [n (%)]

 Yes

26 (28.8)

98 (46.6)

48 (39)

< 0.001c

172 (40.6)

59 (5.8)

129 (78.1)

66 (54)

< 0.001c

254 (65.4)

0.07c

 No

64 (71.1)

112 (53.3)

75 (60.9)

 

251 (59.3)

31 (30.6)

36 (21.8)

56 (45.9)

 

123 (31.7)

 

Former history of abortions [n (%)]

 0

81 (90)

191 (90.9)

118 (95.9)

< 0.001c

390 (92.1)

97 (96)

158 (95.7)

110 (90.1)

< 0.001c

365 (94)

0.2c

  ≥ 1

9 (10)

19 (9)

5 (4.06)

 

33 (7.8)

4 (3.9)

7 (4.2)

12 (9.8)

 

23 (5.9)

 
  1. Data are presented as number [%age], mean ± SD and median [95% population limits]. For both patients and controls, data are classified into age-specific sub-groups, and a statistical difference was tested across different age groups. Data for the total infertile and controls are also subjected to statistical differences, and p > 0.05 considered statistically significant
  2. a= One-way ANOVA; c = χ2-test