Parameters | Infertile Patient Age groups (years) | Control Age groups (years) | Infertile vs. controls p-value | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
25–28 | 29–35 | 36–39 | p- value | Total | 25–28 | 29–35 | 36–39 | p- value | Total | ||
Number of women [n (%)] | 90 (21.2) | 210 (49.6) | 123 (29.07) | – | 423 (100) | 101 (26.01) | 165 (42.5) | 122 (31.4) | – | 388 (100) | – |
Age at menarche (years) n (%)] | |||||||||||
≤ 11 | 12 (3.3) | 35 (16.6) | 24 (19.5) | 0.1c | 71 (16.7) | 8 (7.9) | 11 (6.6) | 14 (11.4) | 0.2c | 33 (8.5) | 0.09c |
12–13 | 49 (54.4) | 108 (51.4) | 59 (47.9) | 216 (51) | 79 (78.2) | 98 (59.3) | 23 (18.8) | 200 (51.5) | |||
13–14 | 10 (11.1) | 45 (25.7) | 31 (14.7) | 86 (20.3) | 12 (11.8) | 41 (24.8) | 81 (66.3) | 134 (34.5) | |||
≥ 15 | 19 (21.1) | 22 (10.4) | 9 (7.3) | 50 (11.8) | 2 (1.9) | 15 (9) | 4 (3.2) | 21 (5.4) | |||
Menstrual Cycle length (days) [mean ± SD] | 33.4 ± 3.1 | 29.9 ± 1.9 | 28.8 ± 1.8 | 0.4a | 30.2 ± 2.0 | 28.9 ± 2.1 | 29.1 ± 2.3 | 30.2 ± 1.9 | 0.3a | 29.9 ± 2.1 | 0.5a |
Frequency of Menses (days) [n (%)] | |||||||||||
Frequent (< 21) | 31 (34.4) | 85 (40.4) | 35 (28.4) | < 0.001c | 151 (35.6) | 1 (0.99) | 0 (0.00) | 1 (0.08) | < 0.001c | 2 (0.51) | 0.01c |
Normal (24–38) | 14 (15.5) | 46 (21.9 | 29 (23.5) | 89 (21) | 100 (99.0) | 164 (99.3) | 121 (99.1) | 385 (99.2) | |||
Infrequent (> 38) | 45 (50) | 79 (37.6) | 59 (47.9) | 183 (43.2) | 0 (0) | 1 (0.6) | 0 (0) | 1 (0.25) | |||
Cycle to Cycle variation over 12 months (days) [n (%)] | |||||||||||
Regular (variation ±2–20 days) | 15 (16.6) | 29 (13.8) | 14 (11.3) | < 0.002c | 58 (13.7) | 101 (100) | 165 (100) | 121 (99.1) | < 0.001c | 387 (99.8) | 0.03c |
Irregular (variations > 20 days) | 75 (83.3) | 190 (90.4) | 109 (88.6) | 374 (88.4) | 0 (0) | 0 (0) | 1 (0) | 1 (0.25) | |||
Duration of blood flow (days) [n (%)]in one episode | |||||||||||
Prolonged (> 8) | 23 (25.5) | 65 (30.9) | 31 (25.2) | < 0.001c | 119 (28.1) | 19 (18.8) | 35 (21.2) | 15 (12.2) | < 0.001c | 69 (17.7) | 0.2c |
Normal (4–8) | 12 (3.3) | 35 (16.6) | 19 (15.4) | 66 (15.6) | 53 (79.2) | 80 (48.4) | 62 (50.8) | 195 (50.2) | |||
Shortened (< 4) | 55 (61.1) | 110 (52.3) | 73 (59.3) | 238 (56.2) | 29 (28.7) | 50 (30.3) | 45 (36.8) | 123 (31.7) | |||
Monthly blood loss (ml) [n (%)] | |||||||||||
Light (< 5) | 23 (25.5) | 73 (34.7) | 15 (12.1) | < 0.001c | 111 (26.2) | 18 (17.8) | 22 (13.3) | 60 (49.1) | < 0.001c | 100 (25.7) | 0.3c |
Normal (5–80) | 25 (27.7) | 49 (23.3) | 10 (8.1) | 84 (19.8) | 55 (54.4) | 101 (61.2) | 52 (42.6) | 208 (53.6) | |||
Heavy (> 80) | 20 (22.2) | 63 (30) | 36 (29.2) | 119 (28.1) | 25 (24.7) | 40 (24.2) | 10 (8.1) | 137 (35.3) | |||
No bleeding | 22 (24.4) | 25 (11.9) | 38 (30.8) | 85 (20) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
Occurrence of Blood clots [n (%)] | |||||||||||
Yes | 26 (28.8) | 98 (46.6) | 48 (39) | < 0.001c | 172 (40.6) | 59 (5.8) | 129 (78.1) | 66 (54) | < 0.001c | 254 (65.4) | 0.07c |
No | 64 (71.1) | 112 (53.3) | 75 (60.9) | 251 (59.3) | 31 (30.6) | 36 (21.8) | 56 (45.9) | 123 (31.7) | |||
Former history of abortions [n (%)] | |||||||||||
0 | 81 (90) | 191 (90.9) | 118 (95.9) | < 0.001c | 390 (92.1) | 97 (96) | 158 (95.7) | 110 (90.1) | < 0.001c | 365 (94) | 0.2c |
≥ 1 | 9 (10) | 19 (9) | 5 (4.06) | 33 (7.8) | 4 (3.9) | 7 (4.2) | 12 (9.8) | 23 (5.9) |