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Table 1 Baseline characteristics of the two groups

From: Risk of miscarriage in women with endometriosis undergoing IVF fresh cycles: a retrospective cohort study

Characteristics

Endometriosis n = 1006

Controls n = 2012

OR (95% CI)

P value

Female’s Age (years)

33.04 ± 3.66

32.83 ± 3.76

–

0.16

Male’s Age (years)

34.75 ± 4.72

34.40 ± 4.85

–

0.06

BMI (kg/m2)

21.94 ± 3.12

22.44 ± 3.20

–

< 0.001

Gravidity [n (%)]

 None

669 (66.5)

968 (48.1)

2.141 (1.829–2.506)

< 0.001

 1

206 (20.5)

501 (24.9)

  

 2

85 (8.4)

319 (15.9)

  

  ≥ 3

46 (4.6)

224 (11.1)

  

 Duration of infertility (years)

4.77 ± 3.38

4.98 ± 3.54

–

0.13

Parity [n (%)]

 None

965 (95.9)

1805 (89.7)

2.699 (1.913–3.808)

< 0.001

 1

41 (4.1)

187 (9.3)

  

 2

0 (0)

20 (1.0)

  

 Day 3 serum FSH (IU/ml)

7.10 ± 3.64

6.98 ± 2.75

–

0.39

Indication to IVF

 Endometriosis

719 (71.47)

   

 Endometriosis +Tubal factor

287 (28.53)

   

 Male factor

 

256 (12.72)

  

 Tubal factor

 

1583 (78.68)

  

 Mixed (without endometriosis)

 

173 (8.60)

  

Regimen of ovarian hyper-stimulation

 Long protocol

719 (71.5)

1244 (61.8)

1.547 (1.313–1.822)

< 0.001

 Flare-up protocol

95 (9.4)

434 (21.6)

  

 GnRH antagonists

186 (18.5)

328 (16.3)

  

 Other

6 (0.6)

6 (0.3)

  

 Duration of stimulation (days)

11.72 ± 2.53

11.36 ± 2.44

–

< 0.001

 Total dose of FSH administered (IU)

3467.85 ± 1448.45

2850.55 ± 1267.95

–

< 0.001

 Estradiol at the time of hCG administration (pg/ml)

2247.77 ± 1601.71

2823.35 ± 1882.31

–

< 0.001

 Total oocytes retrieved

10.07 ± 5.64

12.36 ± 6.02

–

< 0.001

Stage at embryo transfer

 72 h

977 (97.1)

1972 (98.0)

0.683 (0.421–1.109)

0.12

 Blastocysts

29 (2.9)

40 (2.0)

  

 Miscarriage

225 (22.4)

405 (20.1)

1.143 (0.951–1.374)

0.09

  1. Data are expressed as Mean + 1 SD or number (percentage) as appropriate
  2. Data are compared using unpaired Student’s t test or Fisher’s exact test