Characteristics | Endometriosis n = 1006 | Controls n = 2012 | OR (95% CI) | P value |
---|---|---|---|---|
Female’s Age (years) | 33.04 ± 3.66 | 32.83 ± 3.76 | – | 0.16 |
Male’s Age (years) | 34.75 ± 4.72 | 34.40 ± 4.85 | – | 0.06 |
BMI (kg/m2) | 21.94 ± 3.12 | 22.44 ± 3.20 | – | < 0.001 |
Gravidity [n (%)] | ||||
 None | 669 (66.5) | 968 (48.1) | 2.141 (1.829–2.506) | < 0.001 |
 1 | 206 (20.5) | 501 (24.9) |  |  |
 2 | 85 (8.4) | 319 (15.9) |  |  |
  ≥ 3 | 46 (4.6) | 224 (11.1) |  |  |
 Duration of infertility (years) | 4.77 ± 3.38 | 4.98 ± 3.54 | – | 0.13 |
Parity [n (%)] | ||||
 None | 965 (95.9) | 1805 (89.7) | 2.699 (1.913–3.808) | < 0.001 |
 1 | 41 (4.1) | 187 (9.3) |  |  |
 2 | 0 (0) | 20 (1.0) |  |  |
 Day 3 serum FSH (IU/ml) | 7.10 ± 3.64 | 6.98 ± 2.75 | – | 0.39 |
Indication to IVF | ||||
 Endometriosis | 719 (71.47) |  |  |  |
 Endometriosis +Tubal factor | 287 (28.53) |  |  |  |
 Male factor |  | 256 (12.72) |  |  |
 Tubal factor |  | 1583 (78.68) |  |  |
 Mixed (without endometriosis) |  | 173 (8.60) |  |  |
Regimen of ovarian hyper-stimulation | ||||
 Long protocol | 719 (71.5) | 1244 (61.8) | 1.547 (1.313–1.822) | < 0.001 |
 Flare-up protocol | 95 (9.4) | 434 (21.6) |  |  |
 GnRH antagonists | 186 (18.5) | 328 (16.3) |  |  |
 Other | 6 (0.6) | 6 (0.3) |  |  |
 Duration of stimulation (days) | 11.72 ± 2.53 | 11.36 ± 2.44 | – | < 0.001 |
 Total dose of FSH administered (IU) | 3467.85 ± 1448.45 | 2850.55 ± 1267.95 | – | < 0.001 |
 Estradiol at the time of hCG administration (pg/ml) | 2247.77 ± 1601.71 | 2823.35 ± 1882.31 | – | < 0.001 |
 Total oocytes retrieved | 10.07 ± 5.64 | 12.36 ± 6.02 | – | < 0.001 |
Stage at embryo transfer | ||||
 72 h | 977 (97.1) | 1972 (98.0) | 0.683 (0.421–1.109) | 0.12 |
 Blastocysts | 29 (2.9) | 40 (2.0) |  |  |
 Miscarriage | 225 (22.4) | 405 (20.1) | 1.143 (0.951–1.374) | 0.09 |